Sheaff RJ - Search Results

1

Synthesis and Biological Evaluation of a Library of Sulfonamide Analogs of Memantine to Target Glioblastoma.

Philo JE, Caudle JD, Moussa RN, Kampmeyer PM, Hasin TR, Seo DK, Sheaff RJ, Lamar AA. Philo JE, et al. Among authors: sheaff rj. ChemMedChem. 2023 Aug 15;18(16):e202300134. doi: 10.1002/cmdc.202300134. Epub 2023 Jun 14. ChemMedChem. 2023. PMID: 37248422

2

Expansion of a Synthesized Library of N-Benzyl Sulfonamides Derived from an Indole Core to Target Pancreatic Cancer.

Hopkins MD, Costello IJ, Brandeburg ZC, Slay EL, Zanders LA, Dunn CE, Derewonko CA, Davitt CL, Reeder MA, Prichard K, Chiew B, McCluskey A, Sheaff RJ, Lamar AA. Hopkins MD, et al. Among authors: sheaff rj. ChemMedChem. 2023 Oct 4;18(19):e202300265. doi: 10.1002/cmdc.202300265. Epub 2023 Jul 20. ChemMedChem. 2023. PMID: 37421174

3

Synthesis and Biological Evaluation of N-(1H-Indol-6-ylmethyl)benzenesulfonamide Analogs as Metabolic Inhibitors of Mitochondrial ATP Production in Pancreatic Cancer Cells.

Brandeburg ZC, Waheed SA, Derewonko CA, Dunn CE, Pfeiffer EC, Flusche AME, Sheaff RJ, Lamar AA. Brandeburg ZC, et al. Among authors: sheaff rj. ChemMedChem. 2025 Jan 2;20(1):e202400536. doi: 10.1002/cmdc.202400536. Epub 2024 Nov 8. ChemMedChem. 2025. PMID: 39317650

4

Chloroquine-Based Mitochondrial ATP Inhibitors.

Wang Z, Sheaff RJ, Hussaini SR. Wang Z, et al. Among authors: sheaff rj. Molecules. 2023 Jan 24;28(3):1161. doi: 10.3390/molecules28031161. Molecules. 2023. PMID: 36770828 Free PMC article.

5

Synthesis and biological evaluation of N-alkyl sulfonamides derived from polycyclic hydrocarbon scaffolds using a nitrogen-centered radical approach.

Hopkins MD, Witt RC, Flusche AME, Philo JE, Ozmer GL, Purser GH, Sheaff RJ, Lamar AA. Hopkins MD, et al. Among authors: sheaff rj. Org Biomol Chem. 2022 Aug 24;20(33):6680-6693. doi: 10.1039/d2ob01291j. Org Biomol Chem. 2022. PMID: 35950721

6

Development of a Rapid In Vitro Screening Assay Using Metabolic Inhibitors to Detect Highly Selective Anticancer Agents.

Abebe FA, Hopkins MD, Vodnala SN, Sheaff RJ, Lamar AA. Abebe FA, et al. Among authors: sheaff rj. ACS Omega. 2021 Jul 2;6(28):18333-18343. doi: 10.1021/acsomega.1c02203. eCollection 2021 Jul 20. ACS Omega. 2021. PMID: 34308064 Free PMC article.

7

Staphylococcus aureus enhances biofilm formation, aerotolerance, and survival of Campylobacter strains isolated from retail meats.

Karki AB, Ballard K, Harper C, Sheaff RJ, Fakhr MK. Karki AB, et al. Among authors: sheaff rj. Sci Rep. 2021 Jul 5;11(1):13837. doi: 10.1038/s41598-021-91743-w. Sci Rep. 2021. PMID: 34226590 Free PMC article.

8

PhI(OAc)₂ and iodine-mediated synthesis of N-alkyl sulfonamides derived from polycyclic aromatic hydrocarbon scaffolds and determination of their antibacterial and cytotoxic activities.

Hopkins MD, Ozmer GL, Witt RC, Brandeburg ZC, Rogers DA, Keating CE, Petcoff PL, Sheaff RJ, Lamar AA. Hopkins MD, et al. Among authors: sheaff rj. Org Biomol Chem. 2021 Feb 11;19(5):1133-1144. doi: 10.1039/d0ob02429e. Org Biomol Chem. 2021. PMID: 33443507

9

Molecular characterization of megaplasmids encoding the type VI secretion system in Campylobacter jejuni isolated from chicken livers and gizzards.

Marasini D, Karki AB, Bryant JM, Sheaff RJ, Fakhr MK. Marasini D, et al. Among authors: sheaff rj. Sci Rep. 2020 Jul 27;10(1):12514. doi: 10.1038/s41598-020-69155-z. Sci Rep. 2020. PMID: 32719325 Free PMC article.

10

Synthesis and identification of heteroaromatic N-benzyl sulfonamides as potential anticancer agents.

Hopkins MD, Abebe FA, Scott KA, Ozmer GL, Sheir AA, Schroeder LJ, Sheaff RJ, Lamar AA. Hopkins MD, et al. Among authors: sheaff rj. Org Biomol Chem. 2019 Sep 28;17(36):8391-8402. doi: 10.1039/c9ob01694e. Epub 2019 Aug 30. Org Biomol Chem. 2019. PMID: 31469373

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