McCarty KD - Search Results

1

Processive kinetics in the three-step lanosterol 14α-demethylation reaction catalyzed by human cytochrome P450 51A1.

McCarty KD, Sullivan ME, Tateishi Y, Hargrove TY, Lepesheva GI, Guengerich FP. McCarty KD, et al. J Biol Chem. 2023 Jul;299(7):104841. doi: 10.1016/j.jbc.2023.104841. Epub 2023 May 18. J Biol Chem. 2023. PMID: 37209823 Free PMC article.

2

Kinetics of cytochrome P450 3A4 inhibition by heterocyclic drugs defines a general sequential multistep binding process.

Guengerich FP, McCarty KD, Chapman JG. Guengerich FP, et al. Among authors: mccarty kd. J Biol Chem. 2021 Jan-Jun;296:100223. doi: 10.1074/jbc.RA120.016855. Epub 2020 Dec 25. J Biol Chem. 2021. PMID: 33449875 Free PMC article.

3

Tight binding of cytochrome b₅ to cytochrome P450 17A1 is a critical feature of stimulation of C21 steroid lyase activity and androgen synthesis.

Kim D, Kim V, McCarty KD, Guengerich FP. Kim D, et al. Among authors: mccarty kd. J Biol Chem. 2021 Jan-Jun;296:100571. doi: 10.1016/j.jbc.2021.100571. Epub 2021 Mar 20. J Biol Chem. 2021. PMID: 33753170 Free PMC article.

4

Stepwise binding of inhibitors to human cytochrome P450 17A1 and rapid kinetics of inhibition of androgen biosynthesis.

Guengerich FP, McCarty KD, Chapman JG, Tateishi Y. Guengerich FP, et al. Among authors: mccarty kd. J Biol Chem. 2021 Aug;297(2):100969. doi: 10.1016/j.jbc.2021.100969. Epub 2021 Jul 15. J Biol Chem. 2021. PMID: 34273352 Free PMC article.

5

Basis for the discrimination of supercoil handedness during DNA cleavage by human and bacterial type II topoisomerases.

Jian JY, McCarty KD, Byl JAW, Guengerich FP, Neuman KC, Osheroff N. Jian JY, et al. Among authors: mccarty kd. Nucleic Acids Res. 2023 May 8;51(8):3888-3902. doi: 10.1093/nar/gkad190. Nucleic Acids Res. 2023. PMID: 36999602 Free PMC article.

6

Steroid 17α-hydroxylase/17, 20-lyase (cytochrome P450 17A1).

Guengerich FP, McCarty KD, Tateishi Y, Liu L. Guengerich FP, et al. Among authors: mccarty kd. Methods Enzymol. 2023;689:39-63. doi: 10.1016/bs.mie.2023.04.001. Epub 2023 Apr 25. Methods Enzymol. 2023. PMID: 37802581 Free PMC article.

7

The multistep oxidation of cholesterol to pregnenolone by human cytochrome P450 11A1 is highly processive.

McCarty KD, Liu L, Tateishi Y, Wapshott-Stehli HL, Guengerich FP. McCarty KD, et al. J Biol Chem. 2024 Jan;300(1):105495. doi: 10.1016/j.jbc.2023.105495. Epub 2023 Nov 24. J Biol Chem. 2024. PMID: 38006947 Free PMC article.

8

Oxygen-18 Labeling Reveals a Mixed Fe-O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14α-Demethylation.

McCarty KD, Tateishi Y, Hargrove TY, Lepesheva GI, Guengerich FP. McCarty KD, et al. Angew Chem Int Ed Engl. 2024 Feb 26;63(9):e202317711. doi: 10.1002/anie.202317711. Epub 2024 Jan 24. Angew Chem Int Ed Engl. 2024. PMID: 38206808 Free PMC article.

9

Oxygen-18 Labeling Defines a Ferric Peroxide (Compound 0) Mechanism in the Oxidative Deformylation of Aldehydes by Cytochrome P450 2B4.

Tateishi Y, McCarty KD, Martin MV, Guengerich FP. Tateishi Y, et al. Among authors: mccarty kd. ACS Catal. 2024 Jan 31;14(4):2388-2394. doi: 10.1021/acscatal.4c00106. eCollection 2024 Feb 16. ACS Catal. 2024. PMID: 38384943 Free PMC article.

10

Roles of Ferric Peroxide Anion Intermediates (Fe³⁺O₂ ^-, Compound 0) in Cytochrome P450 19A1 Steroid Aromatization and a Cytochrome P450 2B4 Secosteroid Oxidation Model.

Tateishi Y, McCarty KD, Martin MV, Yoshimoto FK, Guengerich FP. Tateishi Y, et al. Among authors: mccarty kd. Angew Chem Int Ed Engl. 2024 Aug 12;63(33):e202406542. doi: 10.1002/anie.202406542. Epub 2024 Jul 17. Angew Chem Int Ed Engl. 2024. PMID: 38820076 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

12 results

Search Page

Filters