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Page 1
Preclinical characterization of the Toll-like receptor 7/8 antagonist MHV370 for lupus therapy.
Hawtin S, André C, Collignon-Zipfel G, Appenzeller S, Bannert B, Baumgartner L, Beck D, Betschart C, Boulay T, Brunner HI, Ceci M, Deane J, Feifel R, Ferrero E, Kyburz D, Lafossas F, Loetscher P, Merz-Stoeckle C, Michellys P, Nuesslein-Hildesheim B, Raulf F, Rush JS, Ruzzante G, Stein T, Zaharevitz S, Wieczorek G, Siegel R, Gergely P, Shisha T, Junt T. Hawtin S, et al. Among authors: feifel r. Cell Rep Med. 2023 May 16;4(5):101036. doi: 10.1016/j.xcrm.2023.101036. Cell Rep Med. 2023. PMID: 37196635 Free PMC article.
First-in-Human Study of the Safety, Pharmacokinetics, and Pharmacodynamics of MHV370, a Dual Inhibitor of Toll-Like Receptors 7 and 8, in Healthy Adults.
Shisha T, Posch MG, Lehmann J, Feifel R, Junt T, Hawtin S, Schuemann J, Avrameas A, Danekula R, Misiolek P, Siegel R, Gergely P. Shisha T, et al. Among authors: feifel r. Eur J Drug Metab Pharmacokinet. 2023 Sep;48(5):553-566. doi: 10.1007/s13318-023-00847-3. Epub 2023 Aug 2. Eur J Drug Metab Pharmacokinet. 2023. PMID: 37532923 Free PMC article. Clinical Trial.
Discovery of the TLR7/8 Antagonist MHV370 for Treatment of Systemic Autoimmune Diseases.
Alper P, Betschart C, André C, Boulay T, Cheng D, Deane J, Faller M, Feifel R, Glatthar R, Han D, Hemmig R, Jiang T, Knoepfel T, Maginnis J, Mutnick D, Pei W, Ruzzante G, Syka P, Zhang G, Zhang Y, Zink F, Zipfel G, Hawtin S, Junt T, Michellys PY. Alper P, et al. Among authors: feifel r. ACS Med Chem Lett. 2023 Jul 31;14(8):1054-1062. doi: 10.1021/acsmedchemlett.3c00136. eCollection 2023 Aug 10. ACS Med Chem Lett. 2023. PMID: 37583811 Free PMC article.
Structure and fragmentation of doubly ionized HNCS.
Wallner M, Olsson E, Ideböhn V, Parriani M, Squibb RJ, Lundberg S, Cole D, Falcinelli S, Stranges S, Brunetti B, Dyke JM, Nyman G, Eland JHD, Hochlaf M, Feifel R. Wallner M, et al. Among authors: feifel r. J Chem Phys. 2024 Jul 28;161(4):044313. doi: 10.1063/5.0215722. J Chem Phys. 2024. PMID: 39056388
Generation of entanglement using a short-wavelength seeded free-electron laser.
Nandi S, Stenquist A, Papoulia A, Olofsson E, Badano L, Bertolino M, Busto D, Callegari C, Carlström S, Danailov MB, Demekhin PV, Di Fraia M, Eng-Johnsson P, Feifel R, Gallician G, Giannessi L, Gisselbrecht M, Manfredda M, Meyer M, Miron C, Peschel J, Plekan O, Prince KC, Squibb RJ, Zangrando M, Zapata F, Zhong S, Dahlström JM. Nandi S, et al. Among authors: feifel r. Sci Adv. 2024 Apr 19;10(16):eado0668. doi: 10.1126/sciadv.ado0668. Epub 2024 Apr 17. Sci Adv. 2024. PMID: 38630815 Free PMC article.
Ultrafast electronic relaxation pathways of the molecular photoswitch quadricyclane.
Borne KD, Cooper JC, Ashfold MNR, Bachmann J, Bhattacharyya S, Boll R, Bonanomi M, Bosch M, Callegari C, Centurion M, Coreno M, Curchod BFE, Danailov MB, Demidovich A, Di Fraia M, Erk B, Faccialà D, Feifel R, Forbes RJG, Hansen CS, Holland DMP, Ingle RA, Lindh R, Ma L, McGhee HG, Muvva SB, Nunes JPF, Odate A, Pathak S, Plekan O, Prince KC, Rebernik P, Rouzée A, Rudenko A, Simoncig A, Squibb RJ, Venkatachalam AS, Vozzi C, Weber PM, Kirrander A, Rolles D. Borne KD, et al. Among authors: feifel r. Nat Chem. 2024 Apr;16(4):499-505. doi: 10.1038/s41557-023-01420-w. Epub 2024 Feb 2. Nat Chem. 2024. PMID: 38307994 Free PMC article.
Isotope effects in dynamics of water isotopologues induced by core ionization at an x-ray free-electron laser.
Guillemin R, Inhester L, Ilchen M, Mazza T, Boll R, Weber T, Eckart S, Grychtol P, Rennhack N, Marchenko T, Velasquez N, Travnikova O, Ismail I, Niskanen J, Kukk E, Trinter F, Gisselbrecht M, Feifel R, Sansone G, Rolles D, Martins M, Meyer M, Simon M, Santra R, Pfeifer T, Jahnke T, Piancastelli MN. Guillemin R, et al. Among authors: feifel r. Struct Dyn. 2023 Oct 3;10(5):054302. doi: 10.1063/4.0000197. eCollection 2023 Sep. Struct Dyn. 2023. PMID: 37799711 Free PMC article.
Femtosecond Polarization Shaping of Free-Electron Laser Pulses.
Perosa G, Wätzel J, Garzella D, Allaria E, Bonanomi M, Danailov MB, Brynes A, Callegari C, De Ninno G, Demidovich A, Di Fraia M, Di Mitri S, Giannessi L, Manfredda M, Novinec L, Pal N, Penco G, Plekan O, Prince KC, Simoncig A, Spampinati S, Spezzani C, Zangrando M, Berakdar J, Feifel R, Squibb RJ, Coffee R, Hemsing E, Roussel E, Sansone G, McNeil BWJ, Ribič PR. Perosa G, et al. Among authors: feifel r. Phys Rev Lett. 2023 Jul 28;131(4):045001. doi: 10.1103/PhysRevLett.131.045001. Phys Rev Lett. 2023. PMID: 37566861 Free article.
Resonant Inner-Shell Photofragmentation of Adamantane (C10H16).
Ganguly S, Gisselbrecht M, Eng-Johnsson P, Feifel R, Díaz-Tendero S, Muchová E, Milosavljević AR, Rousseau P, Maclot S. Ganguly S, et al. Among authors: feifel r. Molecules. 2023 Jul 19;28(14):5510. doi: 10.3390/molecules28145510. Molecules. 2023. PMID: 37513382 Free PMC article.
144 results