Jackrel ME - Search Results

1

Probing the drivers of Staphylococcus aureus biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases.

Howard MK, Miller KR, Sohn BS, Ryan JJ, Xu A, Jackrel ME. Howard MK, et al. Among authors: jackrel me. mBio. 2023 Aug 31;14(4):e0058723. doi: 10.1128/mbio.00587-23. Epub 2023 May 17. mBio. 2023. PMID: 37195208 Free PMC article.

2

Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients.

DeSantis ME, Leung EH, Sweeny EA, Jackrel ME, Cushman-Nick M, Neuhaus-Follini A, Vashist S, Sochor MA, Knight MN, Shorter J. DeSantis ME, et al. Among authors: jackrel me. Cell. 2012 Nov 9;151(4):778-793. doi: 10.1016/j.cell.2012.09.038. Cell. 2012. PMID: 23141537 Free PMC article.

3

A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing.

Champion EA, Lane BH, Jackrel ME, Regan L, Baserga SJ. Champion EA, et al. Among authors: jackrel me. Mol Cell Biol. 2008 Nov;28(21):6547-56. doi: 10.1128/MCB.00906-08. Epub 2008 Aug 25. Mol Cell Biol. 2008. PMID: 18725399 Free PMC article.

4

Shock and awe: unleashing the heat shock response to treat Huntington disease.

Jackrel ME, Shorter J. Jackrel ME, et al. J Clin Invest. 2011 Aug;121(8):2972-5. doi: 10.1172/JCI59190. Epub 2011 Jul 25. J Clin Invest. 2011. PMID: 21785212 Free PMC article.

5

Screening libraries to identify proteins with desired binding activities using a split-GFP reassembly assay.

Jackrel ME, Cortajarena AL, Liu TY, Regan L. Jackrel ME, et al. ACS Chem Biol. 2010 Jun 18;5(6):553-62. doi: 10.1021/cb900272j. ACS Chem Biol. 2010. PMID: 20038141

6

Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma.

Ryan JJ, Sprunger ML, Holthaus K, Shorter J, Jackrel ME. Ryan JJ, et al. Among authors: jackrel me. J Biol Chem. 2019 Jul 19;294(29):11286-11296. doi: 10.1074/jbc.RA119.009494. Epub 2019 Jun 5. J Biol Chem. 2019. PMID: 31171724 Free PMC article.

7

Correction: Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma.

Ryan JJ, Sprunger ML, Holthaus K, Shorter J, Jackrel ME. Ryan JJ, et al. Among authors: jackrel me. J Biol Chem. 2019 Nov 15;294(46):17707. doi: 10.1074/jbc.AAC119.011523. J Biol Chem. 2019. PMID: 31732685 Free PMC article. No abstract available.

8

Functional analysis of proposed substrate-binding residues of Hsp104.

Howard MK, Sohn BS, von Borcke J, Xu A, Jackrel ME. Howard MK, et al. Among authors: jackrel me. PLoS One. 2020 Mar 10;15(3):e0230198. doi: 10.1371/journal.pone.0230198. eCollection 2020. PLoS One. 2020. PMID: 32155221 Free PMC article.

9

Drivers of Hsp104 potentiation revealed by scanning mutagenesis of the middle domain.

Ryan JJ, Bao A, Bell B, Ling C, Jackrel ME. Ryan JJ, et al. Among authors: jackrel me. Protein Sci. 2021 Aug;30(8):1667-1685. doi: 10.1002/pro.4126. Epub 2021 Jun 1. Protein Sci. 2021. PMID: 34010483 Free PMC article.

10

Molecular determinants and modifiers of Matrin-3 toxicity, condensate dynamics, and droplet morphology.

Sprunger ML, Lee K, Sohn BS, Jackrel ME. Sprunger ML, et al. Among authors: jackrel me. iScience. 2022 Feb 11;25(3):103900. doi: 10.1016/j.isci.2022.103900. eCollection 2022 Mar 18. iScience. 2022. PMID: 35252808 Free PMC article.

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