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Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics.
Kim M, McDonald EF, Sabusap CMP, Timalsina B, Joshi D, Hong JS, Rab A, Sorscher EJ, Plate L. Kim M, et al. Among authors: plate l. bioRxiv [Preprint]. 2023 Feb 4:2023.02.04.527134. doi: 10.1101/2023.02.04.527134. bioRxiv. 2023. Update in: J Biol Chem. 2023 Oct;299(10):105242. doi: 10.1016/j.jbc.2023.105242 PMID: 36778339 Free PMC article. Updated. Preprint.
Ribosomal Frameshifting Selectively Modulates the Assembly, Function, and Pharmacological Rescue of a Misfolded CFTR Variant.
Carmody P, Roushar FJ, Tedman A, Wang W, Herwig M, Kim M, McDonald EF, Noguera K, Wong-Roushar J, Poirier JL, Zelt NB, Pockrass BT, McKee AG, Kuntz CP, Raju SV, Plate L, Penn WD, Schlebach JP. Carmody P, et al. Among authors: plate l. bioRxiv [Preprint]. 2024 Jul 23:2023.05.02.539166. doi: 10.1101/2023.05.02.539166. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2414768121. doi: 10.1073/pnas.2414768121 PMID: 39091758 Free PMC article. Updated. Preprint.
Ribosomal frameshifting selectively modulates the assembly, function, and pharmacological rescue of a misfolded CFTR variant.
Carmody PJ, Roushar FJ, Tedman A, Wang W, Herwig M, Kim M, McDonald EF, Noguera K, Wong-Roushar J, Poirier JL, Zelt NB, Pockrass BT, McKee AG, Kuntz CP, Raju SV, Plate L, Penn WD, Schlebach JP. Carmody PJ, et al. Among authors: plate l. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2414768121. doi: 10.1073/pnas.2414768121. Epub 2024 Oct 10. Proc Natl Acad Sci U S A. 2024. PMID: 39388263
95 results