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Design, synthesis, and evaluation of novel pleuromutilin aryl acrylate derivatives as promising broad-spectrum antibiotics especially for combatting multi-drug resistant gram-negative bacteria.
Li M, Li J, Li J, Zhang J, Zhao Y, Li W, Zhang Y, Hu J, Xie X, Zhang D, Li H, Zhao Q, Gao H, Liang C. Li M, et al. Among authors: zhang d, zhang j, zhang y. Eur J Med Chem. 2023 Nov 5;259:115653. doi: 10.1016/j.ejmech.2023.115653. Epub 2023 Jul 22. Eur J Med Chem. 2023. PMID: 37531743
Novel pleuromutilin derivatives conjugated with phenyl-sulfide and boron-containing moieties as potent antibacterial agents against antibiotic-resistant bacteria.
Luo X, Wu G, Feng J, Zhang J, Fu H, Yu H, Han Z, Nie W, Zhu Z, Liu B, Pan W, Li B, Wang Y, Zhang C, Li T, Zhang W, Wu S. Luo X, et al. Among authors: zhang c, zhang w, zhang j. Eur J Med Chem. 2024 Nov 5;277:116745. doi: 10.1016/j.ejmech.2024.116745. Epub 2024 Aug 3. Eur J Med Chem. 2024. PMID: 39106659
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