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MAX mutant small-cell lung cancers exhibit impaired activities of MGA-dependent noncanonical polycomb repressive complex.
Llabata P, Torres-Diz M, Gomez A, Tomas-Daza L, Romero OA, Grego-Bessa J, Llinas-Arias P, Valencia A, Esteller M, Javierre BM, Zhang X, Sanchez-Cespedes M. Llabata P, et al. Among authors: javierre bm. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2024824118. doi: 10.1073/pnas.2024824118. Proc Natl Acad Sci U S A. 2021. PMID: 34493659 Free PMC article.
The HDAC7-TET2 epigenetic axis is essential during early B lymphocyte development.
Azagra A, Meler A, de Barrios O, Tomás-Daza L, Collazo O, Monterde B, Obiols M, Rovirosa L, Vila-Casadesús M, Cabrera-Pasadas M, Gusi-Vives M, Graf T, Varela I, Sardina JL, Javierre BM, Parra M. Azagra A, et al. Among authors: javierre bm. Nucleic Acids Res. 2022 Aug 26;50(15):8471-8490. doi: 10.1093/nar/gkac619. Nucleic Acids Res. 2022. PMID: 35904805 Free PMC article.
Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution.
Tomás-Daza L, Rovirosa L, López-Martí P, Nieto-Aliseda A, Serra F, Planas-Riverola A, Molina O, McDonald R, Ghevaert C, Cuatrecasas E, Costa D, Camós M, Bueno C, Menéndez P, Valencia A, Javierre BM. Tomás-Daza L, et al. Among authors: javierre bm. Nat Commun. 2023 Jan 17;14(1):268. doi: 10.1038/s41467-023-35911-8. Nat Commun. 2023. PMID: 36650138 Free PMC article.
p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response.
Serra F, Nieto-Aliseda A, Fanlo-Escudero L, Rovirosa L, Cabrera-Pasadas M, Lazarenkov A, Urmeneta B, Alcalde-Merino A, Nola EM, Okorokov AL, Fraser P, Graupera M, Castillo SD, Sardina JL, Valencia A, Javierre BM. Serra F, et al. Among authors: javierre bm. Nat Commun. 2024 Apr 1;15(1):2821. doi: 10.1038/s41467-024-46666-1. Nat Commun. 2024. PMID: 38561401 Free PMC article.
RNA sequestration in P-bodies sustains myeloid leukaemia.
Kodali S, Proietti L, Valcarcel G, López-Rubio AV, Pessina P, Eder T, Shi J, Jen A, Lupión-Garcia N, Starner AC, Bartels MD, Cui Y, Sands CM, Planas-Riverola A, Martínez A, Velasco-Hernandez T, Tomás-Daza L, Alber B, Manhart G, Mayer IM, Kollmann K, Fatica A, Menendez P, Shishkova E, Rau RE, Javierre BM, Coon J, Chen Q, Van Nostrand EL, Sardina JL, Grebien F, Di Stefano B. Kodali S, et al. Among authors: javierre bm. Nat Cell Biol. 2024 Oct;26(10):1745-1758. doi: 10.1038/s41556-024-01489-6. Epub 2024 Aug 21. Nat Cell Biol. 2024. PMID: 39169219
The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer.
Fernandez AF, Rosales C, Lopez-Nieva P, Graña O, Ballestar E, Ropero S, Espada J, Melo SA, Lujambio A, Fraga MF, Pino I, Javierre B, Carmona FJ, Acquadro F, Steenbergen RD, Snijders PJ, Meijer CJ, Pineau P, Dejean A, Lloveras B, Capella G, Quer J, Buti M, Esteban JI, Allende H, Rodriguez-Frias F, Castellsague X, Minarovits J, Ponce J, Capello D, Gaidano G, Cigudosa JC, Gomez-Lopez G, Pisano DG, Valencia A, Piris MA, Bosch FX, Cahir-McFarland E, Kieff E, Esteller M. Fernandez AF, et al. Genome Res. 2009 Mar;19(3):438-51. doi: 10.1101/gr.083550.108. Epub 2009 Feb 10. Genome Res. 2009. PMID: 19208682 Free PMC article.
43 results