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Structure-based discovery of conformationally selective inhibitors of the serotonin transporter.
Singh I, Seth A, Billesbølle CB, Braz J, Rodriguiz RM, Roy K, Bekele B, Craik V, Huang XP, Boytsov D, Pogorelov VM, Lak P, O'Donnell H, Sandtner W, Irwin JJ, Roth BL, Basbaum AI, Wetsel WC, Manglik A, Shoichet BK, Rudnick G. Singh I, et al. Among authors: basbaum ai. Cell. 2023 May 11;186(10):2160-2175.e17. doi: 10.1016/j.cell.2023.04.010. Epub 2023 May 2. Cell. 2023. PMID: 37137306 Free PMC article.
Pain and Itch Processing in Aged Mice.
Braz JM, Hamel K, Craik V, Rodriguez-Rosado S, Bhardwaj K, Jewell M, Bieri G, Villeda SA, Basbaum AI. Braz JM, et al. Among authors: basbaum ai. J Pain. 2024 Jan;25(1):53-63. doi: 10.1016/j.jpain.2023.07.018. Epub 2023 Jul 22. J Pain. 2024. PMID: 37482234 Free article.
It all began in Issaquah 50 years ago.
Ballantyne JC, Basbaum AI. Ballantyne JC, et al. Among authors: basbaum ai. Pain. 2024 Nov 1;165(11S):S3-S14. doi: 10.1097/j.pain.0000000000003303. Pain. 2024. PMID: 39560410 Review.
Regulatory T cell-derived enkephalin gates nociception.
Midavaine É, Moraes BC, Benitez J, Rodriguez SR, Braz JM, Kochhar NP, Eckalbar WL, Domingos AI, Pintar JE, Basbaum AI, Kashem SW. Midavaine É, et al. Among authors: basbaum ai. bioRxiv [Preprint]. 2024 Nov 12:2024.05.11.593442. doi: 10.1101/2024.05.11.593442. bioRxiv. 2024. PMID: 38798460 Free PMC article. Preprint.
Large library docking for cannabinoid-1 receptor agonists with reduced side effects.
Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Stein RM, Craik V, Tran NK, Ganapathy S, Liu F, Shiimura Y, Tong F, Ho TC, Radchenko DS, Moroz YS, Rosado SR, Bhardwaj K, Benitez J, Liu Y, Kandasamy H, Normand C, Semache M, Sabbagh L, Glenn I, Irwin JJ, Kumar KK, Makriyannis A, Basbaum AI, Shoichet BK. Tummino TA, et al. Among authors: basbaum ai. bioRxiv [Preprint]. 2024 Feb 28:2023.02.27.530254. doi: 10.1101/2023.02.27.530254. bioRxiv. 2024. PMID: 38328157 Free PMC article. Preprint.
323 results