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m6A epitranscriptomic regulation of tissue homeostasis during primate aging.
Wu Z, Lu M, Liu D, Shi Y, Ren J, Wang S, Jing Y, Zhang S, Zhao Q, Li H, Yu Z, Liu Z, Bi S, Wei T, Yang YG, Xiao J, Belmonte JCI, Qu J, Zhang W, Ci W, Liu GH. Wu Z, et al. Among authors: ren j. Nat Aging. 2023 Jun;3(6):705-721. doi: 10.1038/s43587-023-00393-2. Epub 2023 Apr 6. Nat Aging. 2023. PMID: 37118553
Destabilizing heterochromatin by APOE mediates senescence.
Zhao H, Ji Q, Wu Z, Wang S, Ren J, Yan K, Wang Z, Hu J, Chu Q, Hu H, Cai Y, Wang Q, Huang D, Ji Z, Li J, Belmonte JCI, Song M, Zhang W, Qu J, Liu GH. Zhao H, et al. Among authors: ren j. Nat Aging. 2022 Apr;2(4):303-316. doi: 10.1038/s43587-022-00186-z. Epub 2022 Mar 28. Nat Aging. 2022. PMID: 37117743
A single-cell transcriptomic landscape of primate arterial aging.
Zhang W, Zhang S, Yan P, Ren J, Song M, Li J, Lei J, Pan H, Wang S, Ma X, Ma S, Li H, Sun F, Wan H, Li W, Chan P, Zhou Q, Liu GH, Tang F, Qu J. Zhang W, et al. Among authors: ren j. Nat Commun. 2020 May 5;11(1):2202. doi: 10.1038/s41467-020-15997-0. Nat Commun. 2020. PMID: 32371953 Free PMC article.
SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer.
Bi S, Liu Z, Wu Z, Wang Z, Liu X, Wang S, Ren J, Yao Y, Zhang W, Song M, Liu GH, Qu J. Bi S, et al. Among authors: ren j. Protein Cell. 2020 Jul;11(7):483-504. doi: 10.1007/s13238-020-00728-4. Epub 2020 Jun 6. Protein Cell. 2020. PMID: 32504224 Free PMC article.
Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming.
Yan P, Liu Z, Song M, Wu Z, Xu W, Li K, Ji Q, Wang S, Liu X, Yan K, Esteban CR, Ci W, Belmonte JCI, Xie W, Ren J, Zhang W, Sun Q, Qu J, Liu GH. Yan P, et al. Among authors: ren j. Cell Rep. 2020 Jul 7;32(1):107870. doi: 10.1016/j.celrep.2020.107870. Cell Rep. 2020. PMID: 32640235 Free article.
Single-nucleus transcriptomic landscape of primate hippocampal aging.
Zhang H, Li J, Ren J, Sun S, Ma S, Zhang W, Yu Y, Cai Y, Yan K, Li W, Hu B, Chan P, Zhao GG, Belmonte JCI, Zhou Q, Qu J, Wang S, Liu GH. Zhang H, et al. Among authors: ren j. Protein Cell. 2021 Sep;12(9):695-716. doi: 10.1007/s13238-021-00852-9. Epub 2021 May 30. Protein Cell. 2021. PMID: 34052996 Free PMC article.
BMAL1 moonlighting as a gatekeeper for LINE1 repression and cellular senescence in primates.
Liang C, Ke Q, Liu Z, Ren J, Zhang W, Hu J, Wang Z, Chen H, Xia K, Lai X, Wang Q, Yang K, Li W, Wu Z, Wang C, Yan H, Jiang X, Ji Z, Ma M, Long X, Wang S, Wang H, Sun H, Belmonte JCI, Qu J, Xiang AP, Liu GH. Liang C, et al. Among authors: ren j. Nucleic Acids Res. 2022 Apr 8;50(6):3323-3347. doi: 10.1093/nar/gkac146. Nucleic Acids Res. 2022. PMID: 35286396 Free PMC article.
Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging.
Liu Z, Ji Q, Ren J, Yan P, Wu Z, Wang S, Sun L, Wang Z, Li J, Sun G, Liang C, Sun R, Jiang X, Hu J, Ding Y, Wang Q, Bi S, Wei G, Cao G, Zhao G, Wang H, Zhou Q, Belmonte JCI, Qu J, Zhang W, Liu GH. Liu Z, et al. Among authors: ren j. Dev Cell. 2022 Jun 6;57(11):1347-1368.e12. doi: 10.1016/j.devcel.2022.05.004. Epub 2022 May 24. Dev Cell. 2022. PMID: 35613614 Free article.
ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin.
Hu H, Ji Q, Song M, Ren J, Liu Z, Wang Z, Liu X, Yan K, Hu J, Jing Y, Wang S, Zhang W, Liu GH, Qu J. Hu H, et al. Among authors: ren j. Nucleic Acids Res. 2020 Jun 19;48(11):6001-6018. doi: 10.1093/nar/gkaa425. Nucleic Acids Res. 2020. PMID: 32427330 Free PMC article.
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