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Physiologically based pharmacokinetic/pharmacodynamic model for the prediction of morphine brain disposition and analgesia in adults and children.
Verscheijden LFM, Litjens CHC, Koenderink JB, Mathijssen RHJ, Verbeek MM, de Wildt SN, Russel FGM. Verscheijden LFM, et al. Among authors: litjens chc. PLoS Comput Biol. 2021 Mar 4;17(3):e1008786. doi: 10.1371/journal.pcbi.1008786. eCollection 2021 Mar. PLoS Comput Biol. 2021. PMID: 33661919 Free PMC article.
Protein binding of rifampicin is not saturated when using high-dose rifampicin.
Litjens CHC, Aarnoutse RE, van Ewijk-Beneken Kolmer EWJ, Svensson EM, Colbers A, Burger DM, Boeree MJ, Te Brake LHM; PanACEA-MAMS-TB-01 Team. Litjens CHC, et al. J Antimicrob Chemother. 2019 Apr 1;74(4):986-990. doi: 10.1093/jac/dky527. J Antimicrob Chemother. 2019. PMID: 30597025 Clinical Trial.
Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling.
Litjens CHC, Verscheijden LFM, Bolwerk C, Greupink R, Koenderink JB, van den Broek PHH, van den Heuvel JJMW, Svensson EM, Boeree MJ, Magis-Escurra C, Hoefsloot W, van Crevel R, van Laarhoven A, van Ingen J, Kuipers S, Ruslami R, Burger DM, Russel FGM, Aarnoutse RE, Te Brake LHM. Litjens CHC, et al. J Clin Pharmacol. 2022 Mar;62(3):385-396. doi: 10.1002/jcph.1972. Epub 2021 Oct 25. J Clin Pharmacol. 2022. PMID: 34554580 Free PMC article. Clinical Trial.
Rifampicin Transport by OATP1B1 Variants.
Litjens CHC, van den Heuvel JJMW, Russel FGM, Aarnoutse RE, Te Brake LHM, Koenderink JB. Litjens CHC, et al. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00955-20. doi: 10.1128/AAC.00955-20. Print 2020 Sep 21. Antimicrob Agents Chemother. 2020. PMID: 32690641 Free PMC article.
11 results