Tukov FF - Search Results

1

Review of cardiac safety in onasemnogene abeparvovec gene replacement therapy: translation from preclinical to clinical findings.

Chand DH, Sun R, Diab KA, Kenny D, Tukov FF. Chand DH, et al. Among authors: tukov ff. Gene Ther. 2023 Sep;30(9):685-697. doi: 10.1038/s41434-023-00401-5. Epub 2023 Apr 25. Gene Ther. 2023. PMID: 37095320 Free PMC article. Review.

2

Neurofilament light chain and dorsal root ganglia injury after adeno-associated virus 9 gene therapy in nonhuman primates.

Johnson EW, Sutherland JJ, Meseck E, McElroy C, Chand DH, Tukov FF, Hudry E, Penraat K. Johnson EW, et al. Among authors: tukov ff. Mol Ther Methods Clin Dev. 2022 Dec 26;28:208-219. doi: 10.1016/j.omtm.2022.12.012. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2022. PMID: 36700120 Free PMC article.

3

Liver injury in cynomolgus monkeys following intravenous and intrathecal scAAV9 gene therapy delivery.

Hudry E, Aihara F, Meseck E, Mansfield K, McElroy C, Chand D, Tukov FF, Penraat K. Hudry E, et al. Among authors: tukov ff. Mol Ther. 2023 Oct 4;31(10):2999-3014. doi: 10.1016/j.ymthe.2023.07.020. Epub 2023 Jul 28. Mol Ther. 2023. PMID: 37515322 Free PMC article.

4

Single-Dose Intrathecal Dorsal Root Ganglia Toxicity of Onasemnogene Abeparvovec in Cynomolgus Monkeys.

Tukov FF, Mansfield K, Milton M, Meseck E, Penraat K, Chand D, Hartmann A. Tukov FF, et al. Hum Gene Ther. 2022 Jul;33(13-14):740-756. doi: 10.1089/hum.2021.255. Epub 2022 May 9. Hum Gene Ther. 2022. PMID: 35331006 Free PMC article.

5

Correction to: Clinical Trial and Postmarketing Safety of Onasemnogene Abeparvovec Therapy.

Day JW, Mendell JR, Mercuri E, Finkel RS, Strauss KA, Kleyn A, Tauscher-Wisniewski S, Tukov FF, Reyna SP, Chand DH. Day JW, et al. Among authors: tukov ff. Drug Saf. 2022 Feb;45(2):191-192. doi: 10.1007/s40264-021-01130-7. Drug Saf. 2022. PMID: 34940960 Free PMC article. No abstract available.

6

Clinical Trial and Postmarketing Safety of Onasemnogene Abeparvovec Therapy.

Day JW, Mendell JR, Mercuri E, Finkel RS, Strauss KA, Kleyn A, Tauscher-Wisniewski S, Tukov FF, Reyna SP, Chand DH. Day JW, et al. Among authors: tukov ff. Drug Saf. 2021 Oct;44(10):1109-1119. doi: 10.1007/s40264-021-01107-6. Epub 2021 Aug 12. Drug Saf. 2021. PMID: 34383289 Free PMC article.

7

Hepatotoxicity following administration of onasemnogene abeparvovec (AVXS-101) for the treatment of spinal muscular atrophy.

Chand D, Mohr F, McMillan H, Tukov FF, Montgomery K, Kleyn A, Sun R, Tauscher-Wisniewski S, Kaufmann P, Kullak-Ublick G. Chand D, et al. Among authors: tukov ff. J Hepatol. 2021 Mar;74(3):560-566. doi: 10.1016/j.jhep.2020.11.001. Epub 2020 Nov 10. J Hepatol. 2021. PMID: 33186633 Free article. Clinical Trial.

8

The role of tumor necrosis factor alpha in lipopolysaccharide/ranitidine-induced inflammatory liver injury.

Tukov FF, Luyendyk JP, Ganey PE, Roth RA. Tukov FF, et al. Toxicol Sci. 2007 Nov;100(1):267-80. doi: 10.1093/toxsci/kfm209. Epub 2007 Aug 13. Toxicol Sci. 2007. PMID: 17698507

9

Modeling inflammation-drug interactions in vitro: a rat Kupffer cell-hepatocyte coculture system.

Tukov FF, Maddox JF, Amacher DE, Bobrowski WF, Roth RA, Ganey PE. Tukov FF, et al. Toxicol In Vitro. 2006 Dec;20(8):1488-99. doi: 10.1016/j.tiv.2006.04.005. Epub 2006 May 11. Toxicol In Vitro. 2006. PMID: 16782301

10

Characterization of the role of glutathione in repin-induced mitochondrial dysfunction, oxidative stress and dopaminergic neurotoxicity in rat pheochromocytoma (PC12) cells.

Tukov FF, Rimoldi JM, Matthews JC. Tukov FF, et al. Neurotoxicology. 2004 Dec;25(6):989-99. doi: 10.1016/j.neuro.2004.03.013. Neurotoxicology. 2004. PMID: 15474617

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