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Augmenting TCR signal strength and ICOS costimulation results in metabolically fit and therapeutically potent human CAR Th17 cells.
Wyatt MM, Huff LW, Nelson MH, Neal LR, Medvec AR, Rangel Rivera GO, Smith AS, Rivera Reyes AM, Knochelmann HM, Riley JL, Lesinski GB, Paulos CM. Wyatt MM, et al. Among authors: knochelmann hm. Mol Ther. 2023 Jul 5;31(7):2120-2131. doi: 10.1016/j.ymthe.2023.04.010. Epub 2023 Apr 20. Mol Ther. 2023. PMID: 37081789 Free PMC article.
When worlds collide: Th17 and Treg cells in cancer and autoimmunity.
Knochelmann HM, Dwyer CJ, Bailey SR, Amaya SM, Elston DM, Mazza-McCrann JM, Paulos CM. Knochelmann HM, et al. Cell Mol Immunol. 2018 May;15(5):458-469. doi: 10.1038/s41423-018-0004-4. Epub 2018 Mar 21. Cell Mol Immunol. 2018. PMID: 29563615 Free PMC article. Review.
Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines.
Dwyer CJ, Knochelmann HM, Smith AS, Wyatt MM, Rangel Rivera GO, Arhontoulis DC, Bartee E, Li Z, Rubinstein MP, Paulos CM. Dwyer CJ, et al. Among authors: knochelmann hm. Front Immunol. 2019 Feb 20;10:263. doi: 10.3389/fimmu.2019.00263. eCollection 2019. Front Immunol. 2019. PMID: 30842774 Free PMC article. Review.
IL6 Fuels Durable Memory for Th17 Cell-Mediated Responses to Tumors.
Knochelmann HM, Dwyer CJ, Smith AS, Bowers JS, Wyatt MM, Nelson MH, Rangel Rivera GO, Horton JD, Krieg C, Armeson K, Lesinski GB, Rubinstein MP, Li Z, Paulos CM. Knochelmann HM, et al. Cancer Res. 2020 Sep 15;80(18):3920-3932. doi: 10.1158/0008-5472.CAN-19-3685. Epub 2020 Jun 19. Cancer Res. 2020. PMID: 32561531 Free PMC article.
Identification of human CD4+ T cell populations with distinct antitumor activity.
Nelson MH, Knochelmann HM, Bailey SR, Huff LW, Bowers JS, Majchrzak-Kuligowska K, Wyatt MM, Rubinstein MP, Mehrotra S, Nishimura MI, Armeson KE, Giresi PG, Zilliox MJ, Broxmeyer HE, Paulos CM. Nelson MH, et al. Among authors: knochelmann hm. Sci Adv. 2020 Jul 1;6(27):eaba7443. doi: 10.1126/sciadv.aba7443. Print 2020 Jul. Sci Adv. 2020. PMID: 32937437 Free PMC article.
The evolving landscape of immunotherapy in solid tumors.
Keilson JM, Knochelmann HM, Paulos CM, Kudchadkar RR, Lowe MC. Keilson JM, et al. Among authors: knochelmann hm. J Surg Oncol. 2021 Mar;123(3):798-806. doi: 10.1002/jso.26416. J Surg Oncol. 2021. PMID: 33595890 Free PMC article. Review.
24 results