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The relaxin receptor RXFP1 signals through a mechanism of autoinhibition.
Erlandson SC, Rawson S, Osei-Owusu J, Brock KP, Liu X, Paulo JA, Mintseris J, Gygi SP, Marks DS, Cong X, Kruse AC. Erlandson SC, et al. Nat Chem Biol. 2023 Aug;19(8):1013-1021. doi: 10.1038/s41589-023-01321-6. Epub 2023 Apr 20. Nat Chem Biol. 2023. PMID: 37081311 Free PMC article.
Yeast surface display platform for rapid discovery of conformationally selective nanobodies.
McMahon C, Baier AS, Pascolutti R, Wegrecki M, Zheng S, Ong JX, Erlandson SC, Hilger D, Rasmussen SGF, Ring AM, Manglik A, Kruse AC. McMahon C, et al. Among authors: erlandson sc. Nat Struct Mol Biol. 2018 Mar;25(3):289-296. doi: 10.1038/s41594-018-0028-6. Epub 2018 Feb 12. Nat Struct Mol Biol. 2018. PMID: 29434346 Free PMC article.