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Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies.
Cherry C, Andorko JI, Krishnan K, Mejías JC, Nguyen HH, Stivers KB, Gray-Gaillard EF, Ruta A, Han J, Hamada N, Hamada M, Sturmlechner I, Trewartha S, Michel JH, Davenport Huyer L, Wolf MT, Tam AJ, Peña AN, Keerthivasan S, Le Saux CJ, Fertig EJ, Baker DJ, Housseau F, van Deursen JM, Pardoll DM, Elisseeff JH. Cherry C, et al. Among authors: hamada n, hamada m. Geroscience. 2023 Aug;45(4):2559-2587. doi: 10.1007/s11357-023-00785-7. Epub 2023 Apr 20. Geroscience. 2023. PMID: 37079217 Free PMC article.
Cdc20 is critical for meiosis I and fertility of female mice.
Jin F, Hamada M, Malureanu L, Jeganathan KB, Zhou W, Morbeck DE, van Deursen JM. Jin F, et al. Among authors: hamada m. PLoS Genet. 2010 Sep 30;6(9):e1001147. doi: 10.1371/journal.pgen.1001147. PLoS Genet. 2010. PMID: 20941357 Free PMC article.
Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation.
Kanakkanthara A, Jeganathan KB, Limzerwala JF, Baker DJ, Hamada M, Nam HJ, van Deursen WH, Hamada N, Naylor RM, Becker NA, Davies BA, van Ree JH, Mer G, Shapiro VS, Maher LJ 3rd, Katzmann DJ, van Deursen JM. Kanakkanthara A, et al. Among authors: hamada n, hamada m. Science. 2016 Sep 30;353(6307):1549-1552. doi: 10.1126/science.aaf7463. Science. 2016. PMID: 27708105 Free PMC article.
p21 produces a bioactive secretome that places stressed cells under immunosurveillance.
Sturmlechner I, Zhang C, Sine CC, van Deursen EJ, Jeganathan KB, Hamada N, Grasic J, Friedman D, Stutchman JT, Can I, Hamada M, Lim DY, Lee JH, Ordog T, Laberge RM, Shapiro V, Baker DJ, Li H, van Deursen JM. Sturmlechner I, et al. Among authors: hamada n, hamada m. Science. 2021 Oct 29;374(6567):eabb3420. doi: 10.1126/science.abb3420. Epub 2021 Oct 29. Science. 2021. PMID: 34709885 Free PMC article.
Hyperphosphorylated PTEN exerts oncogenic properties.
van Ree JH, Jeganathan KB, Fierro Velasco RO, Zhang C, Can I, Hamada M, Li H, Baker DJ, van Deursen JM. van Ree JH, et al. Among authors: hamada m. Nat Commun. 2023 May 24;14(1):2983. doi: 10.1038/s41467-023-38740-x. Nat Commun. 2023. PMID: 37225693 Free PMC article.
A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection.
Meehan AM, Saenz DT, Guevera R, Morrison JH, Peretz M, Fadel HJ, Hamada M, van Deursen J, Poeschla EM. Meehan AM, et al. Among authors: hamada m. PLoS Pathog. 2014 Feb 20;10(2):e1003969. doi: 10.1371/journal.ppat.1003969. eCollection 2014 Feb. PLoS Pathog. 2014. PMID: 24586169 Free PMC article.
2,009 results