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Obesity-induced inflammation exacerbates clonal hematopoiesis.
Pasupuleti SK, Ramdas B, Burns SS, Palam LR, Kanumuri R, Kumar R, Pandhiri TR, Dave UP, Yellapu NK, Zhou X, Zhang C, Sandusky GE, Yu Z, Honigberg MC, Bick AG, Griffin GK, Niroula A, Ebert BL, Paczesny S, Natarajan P, Kapur R. Pasupuleti SK, et al. Among authors: palam lr. J Clin Invest. 2023 Jun 1;133(11):e163968. doi: 10.1172/JCI163968. J Clin Invest. 2023. PMID: 37071471 Free PMC article.
Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.
Cai Z, Kotzin JJ, Ramdas B, Chen S, Nelanuthala S, Palam LR, Pandey R, Mali RS, Liu Y, Kelley MR, Sandusky G, Mohseni M, Williams A, Henao-Mejia J, Kapur R. Cai Z, et al. Among authors: palam lr. Cell Stem Cell. 2018 Dec 6;23(6):833-849.e5. doi: 10.1016/j.stem.2018.10.013. Cell Stem Cell. 2018. PMID: 30526882 Free PMC article.
Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells.
Ramdas B, Yuen LD, Palam LR, Patel R, Pasupuleti SK, Jideonwo V, Zhang J, Maguire C, Wong E, Kanumuri R, Zhang C, Sandusky G, Chan RJ, Zhang C, Stieglitz E, Haneline L, Kapur R. Ramdas B, et al. Among authors: palam lr. Mol Ther. 2022 Jul 6;30(7):2505-2521. doi: 10.1016/j.ymthe.2022.04.009. Epub 2022 Apr 20. Mol Ther. 2022. PMID: 35443935 Free PMC article.
Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation.
Garg G, Muschaweckh A, Moreno H, Vasanthakumar A, Floess S, Lepennetier G, Oellinger R, Zhan Y, Regen T, Hiltensperger M, Peter C, Aly L, Knier B, Palam LR, Kapur R, Kaplan MH, Waisman A, Rad R, Schotta G, Huehn J, Kallies A, Korn T. Garg G, et al. Among authors: palam lr. Cell Rep. 2019 Feb 12;26(7):1854-1868.e5. doi: 10.1016/j.celrep.2019.01.070. Cell Rep. 2019. PMID: 30759395 Free PMC article.
20 results