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Page 1
Obesity-induced inflammation exacerbates clonal hematopoiesis.
Pasupuleti SK, Ramdas B, Burns SS, Palam LR, Kanumuri R, Kumar R, Pandhiri TR, Dave UP, Yellapu NK, Zhou X, Zhang C, Sandusky GE, Yu Z, Honigberg MC, Bick AG, Griffin GK, Niroula A, Ebert BL, Paczesny S, Natarajan P, Kapur R. Pasupuleti SK, et al. Among authors: kanumuri r. J Clin Invest. 2023 Jun 1;133(11):e163968. doi: 10.1172/JCI163968. J Clin Invest. 2023. PMID: 37071471 Free PMC article.
Alkynyl nicotinamides show antileukemic activity in drug-resistant acute myeloid leukemia.
Ramdas B, Dayal N, Pandey R, Larocque E, Kanumuri R, Pasupuleti SK, Liu S, Kanellopoulou C, Chu EFY, Mohallem R, Virani S, Chopra G, Aryal UK, Lapidus R, Wan J, Emadi A, Haneline LS, Holtsberg FW, Aman MJ, Sintim HO, Kapur R. Ramdas B, et al. Among authors: kanumuri r. J Clin Invest. 2024 Jun 17;134(12):e169245. doi: 10.1172/JCI169245. J Clin Invest. 2024. PMID: 38950330 Free PMC article.
Oral IRAK-4 Inhibitor CA-4948 Is Blood-Brain Barrier Penetrant and Has Single-Agent Activity against CNS Lymphoma and Melanoma Brain Metastases.
Von Roemeling CA, Doonan BP, Klippel K, Schultz D, Hoang-Minh L, Trivedi V, Li C, Russell RA, Kanumuri RS, Sharma A, Tun HW, Mitchell DA. Von Roemeling CA, et al. Among authors: kanumuri rs. Clin Cancer Res. 2023 May 1;29(9):1751-1762. doi: 10.1158/1078-0432.CCR-22-1682. Clin Cancer Res. 2023. PMID: 36749885 Free PMC article.
Targeting SHP2 phosphatase in hematological malignancies.
Kanumuri R, Kumar Pasupuleti S, Burns SS, Ramdas B, Kapur R. Kanumuri R, et al. Expert Opin Ther Targets. 2022 Apr;26(4):319-332. doi: 10.1080/14728222.2022.2066518. Epub 2022 May 3. Expert Opin Ther Targets. 2022. PMID: 35503226 Free PMC article. Review.
Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells.
Ramdas B, Yuen LD, Palam LR, Patel R, Pasupuleti SK, Jideonwo V, Zhang J, Maguire C, Wong E, Kanumuri R, Zhang C, Sandusky G, Chan RJ, Zhang C, Stieglitz E, Haneline L, Kapur R. Ramdas B, et al. Among authors: kanumuri r. Mol Ther. 2022 Jul 6;30(7):2505-2521. doi: 10.1016/j.ymthe.2022.04.009. Epub 2022 Apr 20. Mol Ther. 2022. PMID: 35443935 Free PMC article.
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies.
Popa R, Kamble SH, Kanumuri RS, King TI, Berthold EC, Intagliata S, Sharma A, McCurdy CR. Popa R, et al. Among authors: kanumuri rs. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Apr 30;1196:123187. doi: 10.1016/j.jchromb.2022.123187. Epub 2022 Mar 5. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 35278810 Free PMC article.
Inflammation-induced PELP1 expression promotes tumorigenesis by activating GM-CSF paracrine secretion in the tumor microenvironment.
Vuttaradhi VK, Ezhil I, Ramani D, Kanumuri R, Raghavan S, Balasubramanian V, Saravanan R, Kanakarajan A, Joseph LD, Pitani RS, Sundaram S, Sjolander A, Venkatraman G, Rayala SK. Vuttaradhi VK, et al. Among authors: kanumuri r. J Biol Chem. 2022 Jan;298(1):101406. doi: 10.1016/j.jbc.2021.101406. Epub 2021 Nov 11. J Biol Chem. 2022. PMID: 34774800 Free PMC article.
22 results