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Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists.
Clark JC, Martin EM, Morán LA, Di Y, Wang X, Zuidscherwoude M, Brown HC, Kavanagh DM, Hummert J, Eble JA, Nieswandt B, Stegner D, Pollitt AY, Herten DP, Tomlinson MG, García A, Watson SP. Clark JC, et al. Among authors: garcia a. Commun Biol. 2023 Apr 7;6(1):376. doi: 10.1038/s42003-023-04766-6. Commun Biol. 2023. PMID: 37029319 Free PMC article.
Analyzing the platelet proteome.
García A, Zitzmann N, Watson SP. García A, et al. Semin Thromb Hemost. 2004 Aug;30(4):485-9. doi: 10.1055/s-2004-833483. Semin Thromb Hemost. 2004. PMID: 15354269 Review.
Applying proteomics technology to platelet research.
García A, Watson SP, Dwek RA, Zitzmann N. García A, et al. Mass Spectrom Rev. 2005 Nov-Dec;24(6):918-30. doi: 10.1002/mas.20047. Mass Spectrom Rev. 2005. PMID: 15599945 Review.
A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.
Suzuki-Inoue K, Fuller GL, García A, Eble JA, Pöhlmann S, Inoue O, Gartner TK, Hughan SC, Pearce AC, Laing GD, Theakston RD, Schweighoffer E, Zitzmann N, Morita T, Tybulewicz VL, Ozaki Y, Watson SP. Suzuki-Inoue K, et al. Among authors: garcia a. Blood. 2006 Jan 15;107(2):542-9. doi: 10.1182/blood-2005-05-1994. Epub 2005 Sep 20. Blood. 2006. PMID: 16174766 Free article.
Isolation and characterization of cotiaractivase, a novel low molecular weight prothrombin activator from the venom of Bothrops cotiara.
Senis YA, Kim PY, Fuller GL, García A, Prabhakar S, Wilkinson MC, Brittan H, Zitzmann N, Wait R, Warrell DA, Watson SP, Kamiguti AS, Theakston RD, Nesheim ME, Laing GD. Senis YA, et al. Among authors: garcia a. Biochim Biophys Acta. 2006 May;1764(5):863-71. doi: 10.1016/j.bbapap.2006.03.004. Epub 2006 Apr 7. Biochim Biophys Acta. 2006. PMID: 16647309
A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein.
Senis YA, Tomlinson MG, García A, Dumon S, Heath VL, Herbert J, Cobbold SP, Spalton JC, Ayman S, Antrobus R, Zitzmann N, Bicknell R, Frampton J, Authi KS, Martin A, Wakelam MJ, Watson SP. Senis YA, et al. Among authors: garcia a. Mol Cell Proteomics. 2007 Mar;6(3):548-64. doi: 10.1074/mcp.D600007-MCP200. Epub 2006 Dec 23. Mol Cell Proteomics. 2007. PMID: 17186946 Free PMC article.
8,498 results