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Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria.
Shuoker B, Pichler MJ, Jin C, Sakanaka H, Wu H, Gascueña AM, Liu J, Nielsen TS, Holgersson J, Nordberg Karlsson E, Juge N, Meier S, Morth JP, Karlsson NG, Abou Hachem M. Shuoker B, et al. Among authors: wu h. Nat Commun. 2023 Apr 1;14(1):1833. doi: 10.1038/s41467-023-37533-6. Nat Commun. 2023. PMID: 37005422 Free PMC article.
Fucosidases from the human gut symbiont Ruminococcus gnavus.
Wu H, Rebello O, Crost EH, Owen CD, Walpole S, Bennati-Granier C, Ndeh D, Monaco S, Hicks T, Colvile A, Urbanowicz PA, Walsh MA, Angulo J, Spencer DIR, Juge N. Wu H, et al. Cell Mol Life Sci. 2021 Jan;78(2):675-693. doi: 10.1007/s00018-020-03514-x. Epub 2020 Apr 24. Cell Mol Life Sci. 2021. PMID: 32333083 Free PMC article.
The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract.
Wu H, Crost EH, Owen CD, van Bakel W, Martínez Gascueña A, Latousakis D, Hicks T, Walpole S, Urbanowicz PA, Ndeh D, Monaco S, Sánchez Salom L, Griffiths R, Reynolds RS, Colvile A, Spencer DIR, Walsh M, Angulo J, Juge N. Wu H, et al. PLoS Biol. 2021 Dec 22;19(12):e3001498. doi: 10.1371/journal.pbio.3001498. eCollection 2021 Dec. PLoS Biol. 2021. PMID: 34936658 Free PMC article.
Exploring the sequence-function space of microbial fucosidases.
Martínez Gascueña A, Wu H, Wang R, Owen CD, Hernando PJ, Monaco S, Penner M, Xing K, Le Gall G, Gardner R, Ndeh D, Urbanowicz PA, Spencer DIR, Walsh M, Angulo J, Juge N. Martínez Gascueña A, et al. Among authors: wu h. Commun Chem. 2024 Jun 18;7(1):137. doi: 10.1038/s42004-024-01212-4. Commun Chem. 2024. PMID: 38890439 Free PMC article.
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