Schmidt S - Search Results

1

Extending the phenotypes associated with TRIO gene variants in a cohort of 25 patients and review of the literature.

Gazdagh G, Hunt D, Gonzalez AMC, Rodriguez MP, Chaudhry A, Madruga M, Vansenne F, Shears D, Curie A, Stattin EL, Anderlid BM, Trajkova S, Angelovska ES, McWilliam C, Wyatt PR, O'Driscoll M, Atton G, Bergman AK, Zacher P, Mewasingh LD, López AG, Alonso-Luengo O, Wai HA, Rohde O, Boiroux P, Debant A, Schmidt S, Baralle D. Gazdagh G, et al. Among authors: schmidt s. Am J Med Genet A. 2023 Jul;191(7):1722-1740. doi: 10.1002/ajmg.a.63194. Epub 2023 Mar 29. Am J Med Genet A. 2023. PMID: 36987741 Review.

2

TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG.

Blangy A, Vignal E, Schmidt S, Debant A, Gauthier-Rouvière C, Fort P. Blangy A, et al. Among authors: schmidt s. J Cell Sci. 2000 Feb;113 ( Pt 4):729-39. doi: 10.1242/jcs.113.4.729. J Cell Sci. 2000. PMID: 10652265

3

The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth.

Estrach S, Schmidt S, Diriong S, Penna A, Blangy A, Fort P, Debant A. Estrach S, et al. Among authors: schmidt s. Curr Biol. 2002 Feb 19;12(4):307-12. doi: 10.1016/s0960-9822(02)00658-9. Curr Biol. 2002. PMID: 11864571 Free article.

4

Identification of the first Rho-GEF inhibitor, TRIPalpha, which targets the RhoA-specific GEF domain of Trio.

Schmidt S, Diriong S, Méry J, Fabbrizio E, Debant A. Schmidt S, et al. FEBS Lett. 2002 Jul 17;523(1-3):35-42. doi: 10.1016/s0014-5793(02)02928-9. FEBS Lett. 2002. PMID: 12123800 Free article.

5

Different regulation of the Trio Dbl-Homology domains by their associated PH domains.

Bellanger JM, Estrach S, Schmidt S, Briançon-Marjollet A, Zugasti O, Fromont S, Debant A. Bellanger JM, et al. Among authors: schmidt s. Biol Cell. 2003 Dec;95(9):625-34. doi: 10.1016/j.biolcel.2003.10.002. Biol Cell. 2003. PMID: 14720465

6

Identification of TRIO-GEFD1 chemical inhibitors using the yeast exchange assay.

Blangy A, Bouquier N, Gauthier-Rouvière C, Schmidt S, Debant A, Leonetti JP, Fort P. Blangy A, et al. Among authors: schmidt s. Biol Cell. 2006 Sep;98(9):511-22. doi: 10.1042/BC20060023. Biol Cell. 2006. PMID: 16686599 Free article.

7

Aptamer-derived peptides as potent inhibitors of the oncogenic RhoGEF Tgat.

Bouquier N, Fromont S, Zeeh JC, Auziol C, Larrousse P, Robert B, Zeghouf M, Cherfils J, Debant A, Schmidt S. Bouquier N, et al. Among authors: schmidt s. Chem Biol. 2009 Apr 24;16(4):391-400. doi: 10.1016/j.chembiol.2009.02.006. Chem Biol. 2009. PMID: 19389625 Free article.

8

Kidins220/ARMS regulates Rac1-dependent neurite outgrowth by direct interaction with the RhoGEF Trio.

Neubrand VE, Thomas C, Schmidt S, Debant A, Schiavo G. Neubrand VE, et al. Among authors: schmidt s. J Cell Sci. 2010 Jun 15;123(Pt 12):2111-23. doi: 10.1242/jcs.064055. J Cell Sci. 2010. PMID: 20519585 Free article.

9

Random mutagenesis of peptide aptamers as an optimization strategy for inhibitor screening.

Bouquier N, Fromont S, Debant A, Schmidt S. Bouquier N, et al. Among authors: schmidt s. Methods Mol Biol. 2012;928:97-118. doi: 10.1007/978-1-62703-008-3_8. Methods Mol Biol. 2012. PMID: 22956136 Free article.

10

Function and regulation of the Rho guanine nucleotide exchange factor Trio.

Schmidt S, Debant A. Schmidt S, et al. Small GTPases. 2014;5:e29769. doi: 10.4161/sgtp.29769. Epub 2014 Jul 2. Small GTPases. 2014. PMID: 24987837 Free PMC article. Review.

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