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Mena regulates nesprin-2 to control actin-nuclear lamina associations, trans-nuclear membrane signalling and gene expression.
Li Mow Chee F, Beernaert B, Griffith BGC, Loftus AEP, Kumar Y, Wills JC, Lee M, Valli J, Wheeler AP, Armstrong JD, Parsons M, Leigh IM, Proby CM, von Kriegsheim A, Bickmore WA, Frame MC, Byron A. Li Mow Chee F, et al. Among authors: von kriegsheim a. Nat Commun. 2023 Mar 23;14(1):1602. doi: 10.1038/s41467-023-37021-x. Nat Commun. 2023. PMID: 36959177 Free PMC article.
Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
Scholz CC, Cavadas MA, Tambuwala MM, Hams E, Rodríguez J, von Kriegsheim A, Cotter P, Bruning U, Fallon PG, Cheong A, Cummins EP, Taylor CT. Scholz CC, et al. Among authors: von kriegsheim a. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18490-5. doi: 10.1073/pnas.1309718110. Epub 2013 Oct 21. Proc Natl Acad Sci U S A. 2013. PMID: 24145445 Free PMC article.
HEATR2 plays a conserved role in assembly of the ciliary motile apparatus.
Diggle CP, Moore DJ, Mali G, zur Lage P, Ait-Lounis A, Schmidts M, Shoemark A, Garcia Munoz A, Halachev MR, Gautier P, Yeyati PL, Bonthron DT, Carr IM, Hayward B, Markham AF, Hope JE, von Kriegsheim A, Mitchison HM, Jackson IJ, Durand B, Reith W, Sheridan E, Jarman AP, Mill P. Diggle CP, et al. Among authors: von kriegsheim a. PLoS Genet. 2014 Sep 18;10(9):e1004577. doi: 10.1371/journal.pgen.1004577. eCollection 2014 Sep. PLoS Genet. 2014. PMID: 25232951 Free PMC article.
Raf family kinases: old dogs have learned new tricks.
Matallanas D, Birtwistle M, Romano D, Zebisch A, Rauch J, von Kriegsheim A, Kolch W. Matallanas D, et al. Among authors: von kriegsheim a. Genes Cancer. 2011 Mar;2(3):232-60. doi: 10.1177/1947601911407323. Genes Cancer. 2011. PMID: 21779496 Free PMC article.
Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity.
von Thun A, Preisinger C, Rath O, Schwarz JP, Ward C, Monsefi N, Rodríguez J, Garcia-Munoz A, Birtwistle M, Bienvenut W, Anderson KI, Kolch W, von Kriegsheim A. von Thun A, et al. Among authors: von kriegsheim a. Mol Cell Biol. 2013 Nov;33(22):4526-37. doi: 10.1128/MCB.00585-13. Epub 2013 Sep 16. Mol Cell Biol. 2013. PMID: 24043311 Free PMC article.
Inferring signaling pathway topologies from multiple perturbation measurements of specific biochemical species.
Xu TR, Vyshemirsky V, Gormand A, von Kriegsheim A, Girolami M, Baillie GS, Ketley D, Dunlop AJ, Milligan G, Houslay MD, Kolch W. Xu TR, et al. Among authors: von kriegsheim a. Sci Signal. 2010 Mar 16;3(113):ra20. doi: 10.1126/scisignal.2000517. Sci Signal. 2010. Corrected and republished in: Sci Signal. 2010;3(134):ra20.. PMID: 20234003 Corrected and republished.
138 results