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The future is now: model-based clinical trial design for Alzheimer's disease.
Romero K, Ito K, Rogers JA, Polhamus D, Qiu R, Stephenson D, Mohs R, Lalonde R, Sinha V, Wang Y, Brown D, Isaac M, Vamvakas S, Hemmings R, Pani L, Bain LJ, Corrigan B; Alzheimer's Disease Neuroimaging Initiative; Coalition Against Major Diseases. Romero K, et al. Clin Pharmacol Ther. 2015 Mar;97(3):210-4. doi: 10.1002/cpt.16. Epub 2014 Dec 27. Clin Pharmacol Ther. 2015. PMID: 25669145 Free PMC article.
Adding Recognition Discriminability Index to the Delayed Recall Is Useful to Predict Conversion from Mild Cognitive Impairment to Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative.
Russo MJ, Campos J, Vázquez S, Sevlever G, Allegri RF; Alzheimer's Disease Neuroimaging Initiative. Russo MJ, et al. Front Aging Neurosci. 2017 Mar 10;9:46. doi: 10.3389/fnagi.2017.00046. eCollection 2017. Front Aging Neurosci. 2017. PMID: 28344552 Free PMC article.
A public resource of baseline data from the Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial.
Reiman EM, Pruzin JJ, Rios-Romenets S, Brown C, Giraldo M, Acosta-Baena N, Tobon C, Hu N, Chen Y, Ghisays V, Enos J, Goradia DD, Lee W, Luo J, Malek-Ahmadi M, Protas H, Thomas RG, Chen K, Su Y, Boker C, Mastroeni D, Alvarez S, Quiroz YT, Langbaum JB, Sink KM, Lopera F, Tariot PN; API ADAD Colombia Trial Group. Reiman EM, et al. Alzheimers Dement. 2023 May;19(5):1938-1946. doi: 10.1002/alz.12843. Epub 2022 Nov 14. Alzheimers Dement. 2023. PMID: 36373344 Free PMC article.
Differential impact of body mass index and leptin on baseline and longitudinal positron emission tomography measurements of the cerebral metabolic rate for glucose in amnestic mild cognitive impairment.
Weise CM, Chen K, Chen Y, Devadas V, Su Y, Reiman EM. Weise CM, et al. Among authors: reiman em. Front Aging Neurosci. 2022 Nov 22;14:1031189. doi: 10.3389/fnagi.2022.1031189. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36570534 Free PMC article.
Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease.
Aguillon D, Langella S, Chen Y, Sanchez JS, Su Y, Vila-Castelar C, Vasquez D, Zetterberg H, Hansson O, Dage JL, Janelidze S, Chen K, Fox-Fuller JT, Aduen P, Martinez JE, Garcia G, Baena A, Guzman C, Johnson KA, Sperling RA, Blennow K, Reiman EM, Lopera F, Quiroz YT. Aguillon D, et al. Among authors: reiman em. Alzheimers Dement. 2023 Jun;19(6):2585-2594. doi: 10.1002/alz.12906. Epub 2022 Dec 26. Alzheimers Dement. 2023. PMID: 36571821 Free PMC article.
671 results