Khullar S - Search Results

1

BOMA, a machine-learning framework for comparative gene expression analysis across brains and organoids.

He C, Kalafut NC, Sandoval SO, Risgaard R, Sirois CL, Yang C, Khullar S, Suzuki M, Huang X, Chang Q, Zhao X, Sousa AMM, Wang D. He C, et al. Among authors: khullar s. Cell Rep Methods. 2023 Feb 15;3(2):100409. doi: 10.1016/j.crmeth.2023.100409. eCollection 2023 Feb 27. Cell Rep Methods. 2023. PMID: 36936070 Free PMC article.

2

Predicting gene regulatory networks from multi-omics to link genetic risk variants and neuroimmunology to Alzheimer's disease phenotypes.

Khullar S, Wang D. Khullar S, et al. bioRxiv [Preprint]. 2021 Sep 20:2021.06.21.449165. doi: 10.1101/2021.06.21.449165. bioRxiv. 2021. PMID: 34189529 Free PMC article. Preprint.

3

Bringing machine learning to research on intellectual and developmental disabilities: taking inspiration from neurological diseases.

Gupta C, Chandrashekar P, Jin T, He C, Khullar S, Chang Q, Wang D. Gupta C, et al. Among authors: khullar s. J Neurodev Disord. 2022 May 2;14(1):28. doi: 10.1186/s11689-022-09438-w. J Neurodev Disord. 2022. PMID: 35501679 Free PMC article. Review.

4

Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer's disease.

Gupta C, Xu J, Jin T, Khullar S, Liu X, Alatkar S, Cheng F, Wang D. Gupta C, et al. Among authors: khullar s. PLoS Comput Biol. 2022 Jul 18;18(7):e1010287. doi: 10.1371/journal.pcbi.1010287. eCollection 2022 Jul. PLoS Comput Biol. 2022. PMID: 35849618 Free PMC article.

5

Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex.

Liu S, Won H, Clarke D, Matoba N, Khullar S, Mu Y, Wang D, Gerstein M. Liu S, et al. Among authors: khullar s. Genome Med. 2022 Nov 24;14(1):133. doi: 10.1186/s13073-022-01133-8. Genome Med. 2022. PMID: 36424644 Free PMC article.

6

Predicting brain-regional gene regulatory networks from multi-omics for Alzheimer's disease phenotypes and Covid-19 severity.

Khullar S, Wang D. Khullar S, et al. Hum Mol Genet. 2023 May 18;32(11):1797-1813. doi: 10.1093/hmg/ddad009. Hum Mol Genet. 2023. PMID: 36648426 Free PMC article.

7

Age-maintained human neurons demonstrate a developmental loss of intrinsic neurite growth ability.

Lear BP, Thompson EAN, Rodriguez K, Arndt ZP, Khullar S, Klosa PC, Lu RJ, Morrow CS, Risgaard R, Peterson ER, Teefy BB, Bhattacharyya A, Sousa AMM, Wang D, Benayoun BA, Moore DL. Lear BP, et al. Among authors: khullar s. bioRxiv [Preprint]. 2023 May 24:2023.05.23.541995. doi: 10.1101/2023.05.23.541995. bioRxiv. 2023. PMID: 37292613 Free PMC article. Preprint.

8

Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development.

Shen M, Sirois CL, Guo Y, Li M, Dong Q, Méndez-Albelo NM, Gao Y, Khullar S, Kissel L, Sandoval SO, Wolkoff NE, Huang SX, Xu Z, Bryan JE, Contractor AM, Korabelnikov T, Glass IA, Doherty D; Birth Defects Research Laboratory; Levine JE, Sousa AMM, Chang Q, Bhattacharyya A, Wang D, Werling DM, Zhao X. Shen M, et al. Among authors: khullar s. Neuron. 2023 Dec 20;111(24):3988-4005.e11. doi: 10.1016/j.neuron.2023.09.014. Epub 2023 Oct 10. Neuron. 2023. PMID: 37820724

9

DeepGAMI: deep biologically guided auxiliary learning for multimodal integration and imputation to improve genotype-phenotype prediction.

Chandrashekar PB, Alatkar S, Wang J, Hoffman GE, He C, Jin T, Khullar S, Bendl J, Fullard JF, Roussos P, Wang D. Chandrashekar PB, et al. Among authors: khullar s. Genome Med. 2023 Oct 31;15(1):88. doi: 10.1186/s13073-023-01248-6. Genome Med. 2023. PMID: 37904203 Free PMC article.

10

NetREm: Network Regression Embeddings reveal cell-type transcription factor coordination for gene regulation.

Khullar S, Huang X, Ramesh R, Svaren J, Wang D. Khullar S, et al. bioRxiv [Preprint]. 2024 May 6:2023.10.25.563769. doi: 10.1101/2023.10.25.563769. bioRxiv. 2024. PMID: 37961577 Free PMC article. Preprint.

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