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Page 1
Single-Cell RNA Sequencing Unifies Developmental Programs of Esophageal and Gastric Intestinal Metaplasia.
Nowicki-Osuch K, Zhuang L, Cheung TS, Black EL, Masqué-Soler N, Devonshire G, Redmond AM, Freeman A, di Pietro M, Pilonis N, Januszewicz W, O'Donovan M, Tavaré S, Shields JD, Fitzgerald RC. Nowicki-Osuch K, et al. Among authors: shields jd. Cancer Discov. 2023 Jun 2;13(6):1346-1363. doi: 10.1158/2159-8290.CD-22-0824. Cancer Discov. 2023. PMID: 36929873 Free PMC article.
Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma.
Riedel A, Helal M, Pedro L, Swietlik JJ, Shorthouse D, Schmitz W, Haas L, Young T, da Costa ASH, Davidson S, Bhandare P, Wolf E, Hall BA, Frezza C, Oskarsson T, Shields JD. Riedel A, et al. Among authors: shields jd. Cancer Immunol Res. 2022 Apr 1;10(4):482-497. doi: 10.1158/2326-6066.CIR-21-0778. Cancer Immunol Res. 2022. PMID: 35362044 Free PMC article.
Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth.
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, Kar G, Vento-Tormo R, Hagai T, Chen X, Haniffa MA, Shields JD, Teichmann SA. Davidson S, et al. Among authors: shields jd. Cell Rep. 2020 May 19;31(7):107628. doi: 10.1016/j.celrep.2020.107628. Cell Rep. 2020. PMID: 32433953 Free PMC article.
Identification of aceNKPs, a committed common progenitor population of the ILC1 and NK cell continuum.
Rodriguez-Rodriguez N, Clark PA, Gogoi M, Ferreira ACF, Kerscher B, Crisp A, Jolin HE, Murphy JE, Sivasubramaniam M, Pedro L, Walker JA, Heycock MWD, Shields JD, Barlow JL, McKenzie ANJ. Rodriguez-Rodriguez N, et al. Among authors: shields jd. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2203454119. doi: 10.1073/pnas.2203454119. Epub 2022 Nov 29. Proc Natl Acad Sci U S A. 2022. PMID: 36442116 Free PMC article.
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation.
Miragaia RJ, Gomes T, Chomka A, Jardine L, Riedel A, Hegazy AN, Whibley N, Tucci A, Chen X, Lindeman I, Emerton G, Krausgruber T, Shields J, Haniffa M, Powrie F, Teichmann SA. Miragaia RJ, et al. Immunity. 2019 Feb 19;50(2):493-504.e7. doi: 10.1016/j.immuni.2019.01.001. Epub 2019 Feb 5. Immunity. 2019. PMID: 30737144 Free PMC article.
Discovery of (2R,4R)-4-((S)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.
Mlynarski SN, Aquila BM, Cantin S, Cook S, Doshi A, Finlay MRV, Gangl ET, Grebe T, Gu C, Kawatkar SP, Petersen J, Pop-Damkov P, Schuller AG, Shao W, Shields JD, Simpson I, Tavakoli S, Tentarelli S, Throner S, Wang H, Wang J, Wu D, Ye Q. Mlynarski SN, et al. Among authors: shields jd. J Med Chem. 2024 Nov 21. doi: 10.1021/acs.jmedchem.4c02309. Online ahead of print. J Med Chem. 2024. PMID: 39572889
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.
Shields JD, Aquila BM, Emmons D, Finlay MRV, Gangl ET, Gu C, Mlynarski SN, Petersen J, Pop-Damkov P, Sha L, Simpson I, Tavakoli S, Tentarelli S, Wang H, Ye Q, Zheng X. Shields JD, et al. J Med Chem. 2024 Nov 14. doi: 10.1021/acs.jmedchem.4c02295. Online ahead of print. J Med Chem. 2024. PMID: 39540340
106 results