Guan KL - Search Results

1

The immunometabolite itaconate stimulates OXGR1 to promote mucociliary clearance during the pulmonary innate immune response.

Zeng YR, Song JB, Wang D, Huang ZX, Zhang C, Sun YP, Shu G, Xiong Y, Guan KL, Ye D, Wang P. Zeng YR, et al. Among authors: guan kl. J Clin Invest. 2023 Mar 15;133(6):e160463. doi: 10.1172/JCI160463. J Clin Invest. 2023. PMID: 36919698 Free PMC article.

2

Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis.

Wang TX, Duan KL, Huang ZX, Xue ZA, Liang JY, Dang Y, Zhang A, Xiong Y, Ding C, Guan KL, Yuan HX. Wang TX, et al. Among authors: guan kl. Life Sci Alliance. 2022 Nov 1;6(1):e202201667. doi: 10.26508/lsa.202201667. Print 2023 Jan. Life Sci Alliance. 2022. PMID: 36319062 Free PMC article.

3

TET2 deficiency sensitizes tumor cells to statins by reducing HMGCS1 expression.

Sun SJ, Ai YJ, Duan KL, Zhang JY, Zhang C, Sun YP, Xiong Y, Guan KL, Yuan HX. Sun SJ, et al. Among authors: guan kl. Oncogene. 2022 Dec;41(50):5385-5396. doi: 10.1038/s41388-022-02531-3. Epub 2022 Nov 8. Oncogene. 2022. PMID: 36348011

4

A Class of Disulfide Compounds Suppresses Ferroptosis by Stabilizing GPX4.

Liu JP, Cen SY, Xue Z, Wang TX, Gao Y, Zheng J, Zhang C, Hu J, Nie S, Xiong Y, Guan KL, Yuan HX. Liu JP, et al. Among authors: guan kl. ACS Chem Biol. 2022 Dec 16;17(12):3389-3406. doi: 10.1021/acschembio.2c00445. Epub 2022 Nov 29. ACS Chem Biol. 2022. PMID: 36446024

5

Itaconate in host inflammation and defense.

Ye D, Wang P, Chen LL, Guan KL, Xiong Y. Ye D, et al. Among authors: guan kl. Trends Endocrinol Metab. 2024 Jul;35(7):586-606. doi: 10.1016/j.tem.2024.02.004. Epub 2024 Mar 5. Trends Endocrinol Metab. 2024. PMID: 38448252 Review.

6

PCK2 maintains intestinal homeostasis and prevents colitis by protecting antibody-secreting cells from oxidative stress.

Duan KL, Wang TX, You JW, Wang HN, Wang ZQ, Huang ZX, Zhang JY, Sun YP, Xiong Y, Guan KL, Ye D, Chen L, Liu R, Yuan HX. Duan KL, et al. Among authors: guan kl. Immunology. 2024 Oct;173(2):339-359. doi: 10.1111/imm.13827. Epub 2024 Jun 27. Immunology. 2024. PMID: 38934051

7

Temsirolimus inhibits FSP1 enzyme activity to induce ferroptosis and restrain liver cancer progression.

Tian RL, Wang TX, Huang ZX, Yang Z, Guan KL, Xiong Y, Wang P, Ye D. Tian RL, et al. Among authors: guan kl. J Mol Cell Biol. 2024 Sep 23:mjae036. doi: 10.1093/jmcb/mjae036. Online ahead of print. J Mol Cell Biol. 2024. PMID: 39313331

8

Acetyl-CoA, protein acetylation, and liver cancer.

Wu Z, Guan KL. Wu Z, et al. Among authors: guan kl. Mol Cell. 2022 Nov 17;82(22):4196-4198. doi: 10.1016/j.molcel.2022.10.015. Mol Cell. 2022. PMID: 36400006 Free article.

9

YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis.

Wu Z, Su J, Li FL, Chen T, Mayner J, Engler A, Ma S, Li Q, Guan KL. Wu Z, et al. Among authors: guan kl. Nat Commun. 2023 Sep 22;14(1):5916. doi: 10.1038/s41467-023-41585-z. Nat Commun. 2023. PMID: 37739954 Free PMC article.

10

The Hippo signalling pathway and its implications in human health and diseases.

Fu M, Hu Y, Lan T, Guan KL, Luo T, Luo M. Fu M, et al. Among authors: guan kl. Signal Transduct Target Ther. 2022 Nov 8;7(1):376. doi: 10.1038/s41392-022-01191-9. Signal Transduct Target Ther. 2022. PMID: 36347846 Free PMC article. Review.

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