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The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection.
Goldswain H, Dong X, Penrice-Randal R, Alruwaili M, Shawli GT, Prince T, Williamson MK, Raghwani J, Randle N, Jones B, Donovan-Banfield I, Salguero FJ, Tree JA, Hall Y, Hartley C, Erdmann M, Bazire J, Jearanaiwitayakul T, Semple MG, Openshaw PJM, Baillie JK; ISARIC4C Investigators; Emmett SR, Digard P, Matthews DA, Turtle L, Darby AC, Davidson AD, Carroll MW, Hiscox JA. Goldswain H, et al. Among authors: semple mg. Genome Biol. 2023 Mar 13;24(1):47. doi: 10.1186/s13059-023-02881-5. Genome Biol. 2023. PMID: 36915185 Free PMC article.
Ebola virus disease sequelae: a challenge that is not going away.
Scott JT, Semple MG. Scott JT, et al. Among authors: semple mg. Lancet Infect Dis. 2017 May;17(5):470-471. doi: 10.1016/S1473-3099(17)30027-0. Epub 2017 Jan 14. Lancet Infect Dis. 2017. PMID: 28094207 Free PMC article. No abstract available.
Reply to Lee and colleagues-Viral posterior uveitis.
Steptoe PJ, Scott JT, Semple MG. Steptoe PJ, et al. Among authors: semple mg. Surv Ophthalmol. 2017 Nov-Dec;62(6):886-887. doi: 10.1016/j.survophthal.2017.06.002. Epub 2017 Jun 15. Surv Ophthalmol. 2017. PMID: 28624250 No abstract available.
Detection, characterization, and enrollment of donors of Ebola convalescent plasma in Sierra Leone.
Tedder RS, Samuel D, Dicks S, Scott JT, Ijaz S, Smith CC, Adaken C, Cole C, Baker S, Edwards T, Kamara P, Kargbo O, Niazi S, Nwakanma D, d'Alessandro U, Burch G, Doughty H, Brown CS, Andrews N, Glynn JR, van Griensven J; Ebola_CP Consortium Investigators; Pollakis G, Paxton WA, Semple MG. Tedder RS, et al. Among authors: semple mg. Transfusion. 2018 May;58(5):1289-1298. doi: 10.1111/trf.14580. Epub 2018 Mar 23. Transfusion. 2018. PMID: 29572862 Free PMC article.
Convalescent plasma therapy for persistent hepatitis E virus infection.
Ankcorn M, Gallacher J, Ijaz S, Taha Y, Harvala H, Maclennan S, Thomson EC, Davis C, Singer JB, da Silva Filipe A, Smollett K, Niebel M, Semple MG, Tedder RS, McPherson S. Ankcorn M, et al. Among authors: semple mg. J Hepatol. 2019 Aug;71(2):434-438. doi: 10.1016/j.jhep.2019.04.008. Epub 2019 May 8. J Hepatol. 2019. PMID: 31075322 Free PMC article. No abstract available.
COVID-19 infection in children.
Sinha IP, Harwood R, Semple MG, Hawcutt DB, Thursfield R, Narayan O, Kenny SE, Viner R, Hewer SL, Southern KW. Sinha IP, et al. Among authors: semple mg. Lancet Respir Med. 2020 May;8(5):446-447. doi: 10.1016/S2213-2600(20)30152-1. Epub 2020 Mar 27. Lancet Respir Med. 2020. PMID: 32224304 Free PMC article. No abstract available.
The UK hibernated pandemic influenza research portfolio: triggered for COVID-19.
Simpson CR, Thomas BD, Challen K, De Angelis D, Fragaszy E, Goodacre S, Hayward A, Lim WS, Rubin GJ, Semple MG, Knight M; NIHR hibernated pandemic studies collaborative group. Simpson CR, et al. Among authors: semple mg. Lancet Infect Dis. 2020 Jul;20(7):767-769. doi: 10.1016/S1473-3099(20)30398-4. Epub 2020 May 15. Lancet Infect Dis. 2020. PMID: 32422199 Free PMC article. No abstract available.
Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study.
Docherty AB, Harrison EM, Green CA, Hardwick HE, Pius R, Norman L, Holden KA, Read JM, Dondelinger F, Carson G, Merson L, Lee J, Plotkin D, Sigfrid L, Halpin S, Jackson C, Gamble C, Horby PW, Nguyen-Van-Tam JS, Ho A, Russell CD, Dunning J, Openshaw PJ, Baillie JK, Semple MG; ISARIC4C investigators. Docherty AB, et al. Among authors: semple mg. BMJ. 2020 May 22;369:m1985. doi: 10.1136/bmj.m1985. BMJ. 2020. PMID: 32444460 Free PMC article.
220 results