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Page 1
Plitidepsin in adult patients with COVID-19 requiring hospital admission: A long-term follow-up analysis.
Varona JF, Landete P, Paredes R, Vates R, Torralba M, Guisado-Vasco P, Porras L, Muñoz P, Gijon P, Ancochea J, Saiz E, Meira F, Jimeno JM, Lopez-Martin JA, Estrada V. Varona JF, et al. Among authors: jimeno jm. Front Cell Infect Microbiol. 2023 Feb 22;13:1097809. doi: 10.3389/fcimb.2023.1097809. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36909731 Free PMC article.
Outcomes and clinical characteristics of the compassionate use of plitidepsin for immunocompromised adult patients with COVID-19.
Aguareles J, Fernández PV, Carralón-González MM, Izquierdo CF, Martí-Ballesteros EM, Fernández VP, Sotres-Fernandez G, García-Delangue T, LaPetra RGV, Sánchez-Manzano MD, Gutiérrez C, García-Coca M, Carnevali-Ruiz D, Barrena-Puertas R, Luque-Pinilla JM, Lloris R, Luepke-Estefan XE, López-Martín JA, Jimeno JM, Guisado-Vasco P. Aguareles J, et al. Among authors: jimeno jm. Int J Infect Dis. 2023 Oct;135:12-17. doi: 10.1016/j.ijid.2023.07.011. Epub 2023 Jul 21. Int J Infect Dis. 2023. PMID: 37481109 Free article.
SARS-CoV-2 variants evolve convergent strategies to remodel the host response.
Bouhaddou M, Reuschl AK, Polacco BJ, Thorne LG, Ummadi MR, Ye C, Rosales R, Pelin A, Batra J, Jang GM, Xu J, Moen JM, Richards AL, Zhou Y, Harjai B, Stevenson E, Rojc A, Ragazzini R, Whelan MVX, Furnon W, De Lorenzo G, Cowton V, Syed AM, Ciling A, Deutsch N, Pirak D, Dowgier G, Mesner D, Turner JL, McGovern BL, Rodriguez ML, Leiva-Rebollo R, Dunham AS, Zhong X, Eckhardt M, Fossati A, Liotta NF, Kehrer T, Cupic A, Rutkowska M, Mena I, Aslam S, Hoffert A, Foussard H, Olwal CO, Huang W, Zwaka T, Pham J, Lyons M, Donohue L, Griffin A, Nugent R, Holden K, Deans R, Aviles P, Lopez-Martin JA, Jimeno JM, Obernier K, Fabius JM, Soucheray M, Hüttenhain R, Jungreis I, Kellis M, Echeverria I, Verba K, Bonfanti P, Beltrao P, Sharan R, Doudna JA, Martinez-Sobrido L, Patel AH, Palmarini M, Miorin L, White K, Swaney DL, Garcia-Sastre A, Jolly C, Zuliani-Alvarez L, Towers GJ, Krogan NJ. Bouhaddou M, et al. Among authors: jimeno jm. Cell. 2023 Oct 12;186(21):4597-4614.e26. doi: 10.1016/j.cell.2023.08.026. Epub 2023 Sep 21. Cell. 2023. PMID: 37738970 Free PMC article.
Outcomes and clinical characteristics of the compassionate use of plitidepsin in COVID-19 patients with solid tumours, haematological malignancies or anti-CD20 antibody treatment.
Aguareles J, Villares Fernández P, Forné C, Martí-Ballesteros EM, Pradillo Fernández V, Sotres-Fernandez G, de la Fuente-Burguera A, Navarro-San Francisco C, Buzón-Martín LM, García-Delangue T, Aiello FT, Carnevali-Ruiz D, Lloris R, Luepke-Estefan XE, López-Martín JA, Jimeno JM, García-Casas A, Guisado-Vasco P. Aguareles J, et al. Among authors: jimeno jm. Infect Dis (Lond). 2024 Jul;56(7):575-580. doi: 10.1080/23744235.2024.2351043. Epub 2024 May 14. Infect Dis (Lond). 2024. PMID: 38743059
Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.
Varona JF, Landete P, Lopez-Martin JA, Estrada V, Paredes R, Guisado-Vasco P, Fernandez de Orueta L, Torralba M, Fortun J, Vates R, Barberan J, Clotet B, Ancochea J, Carnevali D, Cabello N, Porras L, Gijon P, Monereo A, Abad D, Zuñiga S, Sola I, Rodon J, Vergara-Alert J, Izquierdo-Useros N, Fudio S, Pontes MJ, de Rivas B, Giron de Velasco P, Nieto A, Gomez J, Aviles P, Lubomirov R, Belgrano A, Sopesen B, White KM, Rosales R, Yildiz S, Reuschl AK, Thorne LG, Jolly C, Towers GJ, Zuliani-Alvarez L, Bouhaddou M, Obernier K, McGovern BL, Rodriguez ML, Enjuanes L, Fernandez-Sousa JM, Krogan NJ, Jimeno JM, Garcia-Sastre A. Varona JF, et al. Among authors: jimeno jm. Life Sci Alliance. 2022 Jan 10;5(4):e202101200. doi: 10.26508/lsa.202101200. Print 2022 Apr. Life Sci Alliance. 2022. PMID: 35012962 Free PMC article. Clinical Trial.
Plitidepsin as a successful rescue treatment for prolonged viral SARS-CoV-2 replication in a patient with previous anti-CD20 monoclonal antibody-mediated B cell depletion and chronic lymphocytic leukemia.
Guisado-Vasco P, Carralón-González MM, Aguareles-Gorines J, Martí-Ballesteros EM, Sánchez-Manzano MD, Carnevali-Ruiz D, García-Coca M, Barrena-Puertas R, de Viedma RG, Luque-Pinilla JM, Sotres-Fernandez G, Fernández-Sousa JM, Luepke-Estefan XE, López-Martín JA, Jimeno JM. Guisado-Vasco P, et al. Among authors: jimeno jm. J Hematol Oncol. 2022 Jan 10;15(1):4. doi: 10.1186/s13045-021-01220-0. J Hematol Oncol. 2022. PMID: 35012608 Free PMC article.
Plitidepsin for the management of a cancer patient infected with SARS-CoV-2 while receiving chemotherapy.
Guisado-Vasco P, González-Cortijo L, D'Errico G, Serrera-Alvarez A, Sotres-Fernandez G, García-Coca M, Fernández-Sousa JM, Luepke-Estefan XE, López-Martín JA, Jimeno JM. Guisado-Vasco P, et al. Among authors: jimeno jm. Ann Oncol. 2021 Oct;32(10):1295-1297. doi: 10.1016/j.annonc.2021.07.003. Epub 2021 Jul 7. Ann Oncol. 2021. PMID: 34242743 Free PMC article. No abstract available.
Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.
Varona JF, Landete P, Lopez-Martin JA, Estrada V, Paredes R, Guisado-Vasco P, de Orueta LF, Torralba M, Fortún J, Vates R, Barberán J, Clotet B, Ancochea J, Carnevali D, Cabello N, Porras L, Gijón P, Monereo A, Abad D, Zúñiga S, Sola I, Rodon J, Izquierdo-Useros N, Fudio S, Pontes MJ, de Rivas B, Girón de Velasco P, Sopesén B, Nieto A, Gómez J, Avilés P, Lubomirov R, White KM, Rosales R, Yildiz S, Reuschl AK, Thorne LG, Jolly C, Towers GJ, Zuliani-Alvarez L, Bouhaddou M, Obernier K, Enjuanes L, Fernández-Sousa JM; Plitidepsin – COVID - 19 Study Group; Krogan NJ, Jimeno JM, García-Sastre A. Varona JF, et al. Among authors: jimeno jm. medRxiv [Preprint]. 2021 May 25:2021.05.25.21257505. doi: 10.1101/2021.05.25.21257505. medRxiv. 2021. Update in: Life Sci Alliance. 2022 Jan 10;5(4):e202101200. doi: 10.26508/lsa.202101200 PMID: 34075384 Free PMC article. Updated. Preprint.
42 results