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Page 1
Plasma biomarkers identify older adults at risk of Alzheimer's disease and related dementias in a real-world population-based cohort.
Ferreira PCL, Zhang Y, Snitz B, Chang CH, Bellaver B, Jacobsen E, Kamboh MI, Zetterberg H, Blennow K, Pascoal TA, Villemagne VL, Ganguli M, Karikari TK. Ferreira PCL, et al. Among authors: bellaver b. Alzheimers Dement. 2023 Oct;19(10):4507-4519. doi: 10.1002/alz.12986. Epub 2023 Mar 6. Alzheimers Dement. 2023. PMID: 36876954 Free PMC article.
Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials.
Ferreira PCL, Ferrari-Souza JP, Tissot C, Bellaver B, Leffa DT, Lussier F, Povala G, Therriault J, Benedet AL, Ashton NJ, Cohen AD, Lopez OL, Tudorascu DL, Klunk WE, Soucy JP, Gauthier S, Villemagne V, Zetterberg H, Blennow K, Rosa-Neto P, Zimmer ER, Karikari TK, Pascoal TA; Alzheimer's Disease Neuroimaging Initiative. Ferreira PCL, et al. Among authors: bellaver b. Neurology. 2023 Jul 4;101(1):38-45. doi: 10.1212/WNL.0000000000207115. Epub 2023 Mar 6. Neurology. 2023. PMID: 36878697 Free PMC article.
APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles.
Ferrari-Souza JP, Lussier FZ, Leffa DT, Therriault J, Tissot C, Bellaver B, Ferreira PCL, Malpetti M, Wang YT, Povala G, Benedet AL, Ashton NJ, Chamoun M, Servaes S, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, O'Brien JT, Rowe JB, Cohen AD, Lopez OL, Tudorascu DL, Karikari TK, Klunk WE, Villemagne VL, Soucy JP, Gauthier S, Souza DO, Zetterberg H, Blennow K, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Among authors: bellaver b. Sci Adv. 2023 Apr 5;9(14):eade1474. doi: 10.1126/sciadv.ade1474. Epub 2023 Apr 5. Sci Adv. 2023. PMID: 37018391 Free PMC article.
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease.
Bellaver B, Povala G, Ferreira PCL, Ferrari-Souza JP, Leffa DT, Lussier FZ, Benedet AL, Ashton NJ, Triana-Baltzer G, Kolb HC, Tissot C, Therriault J, Servaes S, Stevenson J, Rahmouni N, Lopez OL, Tudorascu DL, Villemagne VL, Ikonomovic MD, Gauthier S, Zimmer ER, Zetterberg H, Blennow K, Aizenstein HJ, Klunk WE, Snitz BE, Maki P, Thurston RC, Cohen AD, Ganguli M, Karikari TK, Rosa-Neto P, Pascoal TA. Bellaver B, et al. Nat Med. 2023 Jul;29(7):1775-1781. doi: 10.1038/s41591-023-02380-x. Epub 2023 May 29. Nat Med. 2023. PMID: 37248300 Free PMC article.
APOEε4 potentiates amyloid β effects on longitudinal tau pathology.
Ferrari-Souza JP, Bellaver B, Ferreira PCL, Benedet AL, Povala G, Lussier FZ, Leffa DT, Therriault J, Tissot C, Soares C, Wang YT, Chamoun M, Servaes S, Macedo AC, Vermeiren M, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, Cohen A, Lopez OL, Klunk WE, Soucy JP, Gauthier S, Souza DO, Triana-Baltzer G, Saad ZS, Kolb HC, Karikari TK, Villemagne VL, Tudorascu DL, Ashton NJ, Zetterberg H, Blennow K, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Among authors: bellaver b. Nat Aging. 2023 Oct;3(10):1210-1218. doi: 10.1038/s43587-023-00490-2. Epub 2023 Sep 25. Nat Aging. 2023. PMID: 37749258 Free PMC article.
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease.
Gonzalez-Ortiz F, Ferreira PCL, González-Escalante A, Montoliu-Gaya L, Ortiz-Romero P, Kac PR, Turton M, Kvartsberg H, Ashton NJ, Zetterberg H, Harrison P, Bellaver B, Povala G, Villemagne VL, Pascoal TA, Ganguli M, Cohen AD, Minguillon C, Contador J, Suárez-Calvet M, Karikari TK, Blennow K. Gonzalez-Ortiz F, et al. Among authors: bellaver b. Alzheimers Dement. 2024 Feb;20(2):1239-1249. doi: 10.1002/alz.13525. Epub 2023 Nov 17. Alzheimers Dement. 2024. PMID: 37975513 Free PMC article.
Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease.
Zeng X, Lafferty TK, Sehrawat A, Chen Y, Ferreira PCL, Bellaver B, Povala G, Kamboh MI, Klunk WE, Cohen AD, Lopez OL, Ikonomovic MD, Pascoal TA, Ganguli M, Villemagne VL, Snitz BE, Karikari TK. Zeng X, et al. Among authors: bellaver b. Mol Neurodegener. 2024 Oct 10;19(1):68. doi: 10.1186/s13024-024-00753-5. Mol Neurodegener. 2024. PMID: 39385222 Free PMC article.
Insights into the use of biomarkers in clinical trials in Alzheimer's disease.
Pascoal TA, Aguzzoli CS, Lussier FZ, Crivelli L, Suemoto CK, Fortea J, Rosa-Neto P, Zimmer ER, Ferreira PCL, Bellaver B. Pascoal TA, et al. Among authors: bellaver b. EBioMedicine. 2024 Oct;108:105322. doi: 10.1016/j.ebiom.2024.105322. Epub 2024 Oct 3. EBioMedicine. 2024. PMID: 39366844 Free article. Review.
Modeling the progression of neuropsychiatric symptoms in Alzheimer's disease with PET-based Braak staging.
Macedo AC, Therriault J, Tissot C, Aumont É, Servaes S, Rahmouni N, Fernandez-Arias J, Lussier FZ, Wang YT, Ng KP, Vermeiren M, Bezgin G, Socualaya KQ, Stevenson J, Hosseini SA, Chamoun M, Ferrari-Souza JP, Ferreira PCL, Bellaver B, Leffa DT, Vitali P, Zimmer ER, Ismail Z, Pascoal TA, Gauthier S, Rosa-Neto P. Macedo AC, et al. Among authors: bellaver b. Neurobiol Aging. 2024 Dec;144:127-137. doi: 10.1016/j.neurobiolaging.2024.09.009. Epub 2024 Sep 20. Neurobiol Aging. 2024. PMID: 39326302 Free article.
Glial reactivity is linked to synaptic dysfunction across the aging and Alzheimer's disease spectrum.
Pascoal T, Rohden F, Ferreira P, Bellaver B, Ferrari-Souza JP, Aguzzoli C, Soares C, Abbas S, Zalzale H, Povala G, Lussier F, Leffa D, Bauer-Negrini G, Rahmouni N, Tissot C, Therriault JT, Servaes S, Stevenson J, Benedet A, Ashton N, Karikari T, Tudorascu D, Zetterberg H, Blennow K, Zimmer E, Souza D, Rosa-Neto P. Pascoal T, et al. Among authors: bellaver b. Res Sq [Preprint]. 2024 Aug 12:rs.3.rs-4782732. doi: 10.21203/rs.3.rs-4782732/v1. Res Sq. 2024. PMID: 39184102 Free PMC article. Preprint.
63 results