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A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins.
Castelli LM, Lin YH, Sanchez-Martinez A, Gül A, Mohd Imran K, Higginbottom A, Upadhyay SK, Márkus NM, Rua Martins R, Cooper-Knock J, Montmasson C, Cohen R, Walton A, Bauer CS, De Vos KJ, Mead RJ, Azzouz M, Dominguez C, Ferraiuolo L, Shaw PJ, Whitworth AJ, Hautbergue GM. Castelli LM, et al. Among authors: cohen r. Sci Transl Med. 2023 Mar;15(685):eabo3823. doi: 10.1126/scitranslmed.abo3823. Epub 2023 Mar 1. Sci Transl Med. 2023. PMID: 36857431
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD.
Bauer CS, Cohen RN, Sironi F, Livesey MR, Gillingwater TH, Highley JR, Fillingham DJ, Coldicott I, Smith EF, Gibson YB, Webster CP, Grierson AJ, Bendotti C, De Vos KJ. Bauer CS, et al. Among authors: cohen rn. Acta Neuropathol. 2022 Sep;144(3):437-464. doi: 10.1007/s00401-022-02470-z. Epub 2022 Jul 25. Acta Neuropathol. 2022. PMID: 35876881 Free PMC article.
Refining the Prothrombotic State in Atrial Fibrillation with Left Atrial Appendage 3D Echocardiography.
Soulat-Dufour L, Lang S, Ponnaiah M, Simon T, Ederhy S, Adavane-Scheuble S, Chauvet-Droit M, Capderou E, Arnaud C, Sotto E, Cohen R, d'Izarny Gargas T, Scheuble A, Hammoudi N, Beraud AS, Addetia K, Boccara F, Lang RM, Cohen A. Soulat-Dufour L, et al. Among authors: cohen r. J Am Soc Echocardiogr. 2024 Nov 1:S0894-7317(24)00560-1. doi: 10.1016/j.echo.2024.10.014. Online ahead of print. J Am Soc Echocardiogr. 2024. PMID: 39489403 No abstract available.
6,591 results