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Page 1
Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases.
Yuan S, Wang L, Zhang H, Xu F, Zhou X, Yu L, Sun J, Chen J, Ying H, Xu X, Yu Y, Spiliopoulou A, Shen X, Wilson J, Gill D, Theodoratou E, Larsson SC, Li X. Yuan S, et al. Among authors: spiliopoulou a. EBioMedicine. 2023 Mar;89:104488. doi: 10.1016/j.ebiom.2023.104488. Epub 2023 Feb 24. EBioMedicine. 2023. PMID: 36842216 Free PMC article.
Reply to 'Misestimation of heritability and prediction accuracy of male-pattern baldness'.
Pirastu N, Joshi PK, de Vries PS, Cornelis MC, Keum N, Franceschini N, Colombo M, Giovannucci EL, Spiliopoulou A, Franke L, North KE, Kraft P, Morrison AC, Esko T, Wilson JF. Pirastu N, et al. Among authors: spiliopoulou a. Nat Commun. 2018 Jun 29;9(1):2538. doi: 10.1038/s41467-018-04808-2. Nat Commun. 2018. PMID: 29959316 Free PMC article. No abstract available.
MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank.
Li X, Meng X, Spiliopoulou A, Timofeeva M, Wei WQ, Gifford A, Shen X, He Y, Varley T, McKeigue P, Tzoulaki I, Wright AF, Joshi P, Denny JC, Campbell H, Theodoratou E. Li X, et al. Among authors: spiliopoulou a. Ann Rheum Dis. 2018 Jul;77(7):1039-1047. doi: 10.1136/annrheumdis-2017-212534. Epub 2018 Feb 6. Ann Rheum Dis. 2018. PMID: 29437585 Free PMC article.
Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study.
He Y, Timofeeva M, Farrington SM, Vaughan-Shaw P, Svinti V, Walker M, Zgaga L, Meng X, Li X, Spiliopoulou A, Jiang X, Hyppönen E, Kraft P, Kiel DP; SUNLIGHT consortium; Hayward C, Campbell A, Porteous D, Vucic K, Kirac I, Filipovic M, Harris SE, Deary IJ, Houlston R, Tomlinson IP, Campbell H, Theodoratou E, Dunlop MG. He Y, et al. Among authors: spiliopoulou a. BMC Med. 2018 Aug 14;16(1):142. doi: 10.1186/s12916-018-1119-2. BMC Med. 2018. PMID: 30103784 Free PMC article. Clinical Trial.
Phenome-wide Mendelian-randomization study of genetically determined vitamin D on multiple health outcomes using the UK Biobank study.
Meng X, Li X, Timofeeva MN, He Y, Spiliopoulou A, Wei WQ, Gifford A, Wu H, Varley T, Joshi P, Denny JC, Farrington SM, Zgaga L, Dunlop MG, McKeigue P, Campbell H, Theodoratou E. Meng X, et al. Among authors: spiliopoulou a. Int J Epidemiol. 2019 Oct 1;48(5):1425-1434. doi: 10.1093/ije/dyz182. Int J Epidemiol. 2019. PMID: 31518429 Free PMC article.
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.
Li X, Meng X, He Y, Spiliopoulou A, Timofeeva M, Wei WQ, Gifford A, Yang T, Varley T, Tzoulaki I, Joshi P, Denny JC, Mckeigue P, Campbell H, Theodoratou E. Li X, et al. Among authors: spiliopoulou a. PLoS Med. 2019 Oct 18;16(10):e1002937. doi: 10.1371/journal.pmed.1002937. eCollection 2019 Oct. PLoS Med. 2019. PMID: 31626644 Free PMC article.
Prediction of colorectal cancer risk based on profiling with common genetic variants.
Li X, Timofeeva M, Spiliopoulou A, McKeigue P, He Y, Zhang X, Svinti V, Campbell H, Houlston RS, Tomlinson IPM, Farrington SM, Dunlop MG, Theodoratou E. Li X, et al. Among authors: spiliopoulou a. Int J Cancer. 2020 Dec 15;147(12):3431-3437. doi: 10.1002/ijc.33191. Epub 2020 Jul 20. Int J Cancer. 2020. PMID: 32638365 Free article.
Alcohol consumption, blood DNA methylation and breast cancer: a Mendelian randomisation study.
Zhou X, Yu L, Wang L, Xiao J, Sun J, Zhou Y, Xu X, Xu W, Spiliopoulou A, Timofeeva M, Zhang X, He Y, Yang H, Campbell H, Zhang B, Zhu Y, Theodoratou E, Li X. Zhou X, et al. Among authors: spiliopoulou a. Eur J Epidemiol. 2022 Jul;37(7):701-712. doi: 10.1007/s10654-022-00886-1. Epub 2022 Jun 16. Eur J Epidemiol. 2022. PMID: 35708873 Free PMC article.
Exploring the cross-cancer effect of smoking and its fingerprints in blood DNA methylation on multiple cancers: A Mendelian randomization study.
Zhou Y, Zhou X, Sun J, Wang L, Zhao J, Chen J, Yuan S, He Y, Timofeeva M, Spiliopoulou A, Mesa-Eguiagaray I, Farrington SM, Ding K, Dunlop MG, Qian X, Theodoratou E, Li X. Zhou Y, et al. Among authors: spiliopoulou a. Int J Cancer. 2023 Oct 15;153(8):1477-1486. doi: 10.1002/ijc.34656. Epub 2023 Jul 14. Int J Cancer. 2023. PMID: 37449541 Free PMC article.
74 results