Jochmans D - Search Results

1

Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells.

Vanhoutte R, Barniol-Xicota M, Chiu W, Vangeel L, Jochmans D, De Jonghe S, Zidane H, Barr HM, London N, Neyts J, Verhelst SHL. Vanhoutte R, et al. Among authors: jochmans d. Chem Sci. 2023 Jan 6;14(7):1666-1672. doi: 10.1039/d2sc04147b. eCollection 2023 Feb 15. Chem Sci. 2023. PMID: 36819852 Free PMC article.

2

MAPPIT (MAmmalian Protein-Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells.

Pattyn E, Lavens D, Van der Heyden J, Verhee A, Lievens S, Lemmens I, Hallenberger S, Jochmans D, Tavernier J. Pattyn E, et al. Among authors: jochmans d. J Virol Methods. 2008 Oct;153(1):7-15. doi: 10.1016/j.jviromet.2008.06.021. Epub 2008 Jul 30. J Virol Methods. 2008. PMID: 18640157

3

Identification of HIV-1 reverse transcriptase inhibitors using a scintillation proximity assay.

Van Schoubroeck B, Van Loock M, Ivens T, Dehertogh P, Jochmans D, Dams G. Van Schoubroeck B, et al. Among authors: jochmans d. Methods Mol Biol. 2013;1030:19-24. doi: 10.1007/978-1-62703-484-5_3. Methods Mol Biol. 2013. PMID: 23821257

4

Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells.

Natesampillai S, Nie Z, Cummins NW, Jochmans D, Bren GD, Angel JB, Badley AD. Natesampillai S, et al. Among authors: jochmans d. PLoS Pathog. 2010 Nov 24;6(11):e1001213. doi: 10.1371/journal.ppat.1001213. PLoS Pathog. 2010. PMID: 21124822 Free PMC article.

5

Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors.

Goethals O, Clayton R, Van Ginderen M, Vereycken I, Wagemans E, Geluykens P, Dockx K, Strijbos R, Smits V, Vos A, Meersseman G, Jochmans D, Vermeire K, Schols D, Hallenberger S, Hertogs K. Goethals O, et al. Among authors: jochmans d. J Virol. 2008 Nov;82(21):10366-74. doi: 10.1128/JVI.00470-08. Epub 2008 Aug 20. J Virol. 2008. PMID: 18715920 Free PMC article.

6

Formation of a quaternary complex of HIV-1 reverse transcriptase with a nucleotide-competing inhibitor and its ATP enhancer.

Ehteshami M, Nijhuis M, Bernatchez JA, Ablenas CJ, McCormick S, de Jong D, Jochmans D, Götte M. Ehteshami M, et al. Among authors: jochmans d. J Biol Chem. 2013 Jun 14;288(24):17336-46. doi: 10.1074/jbc.M112.433441. Epub 2013 Apr 18. J Biol Chem. 2013. PMID: 23598281 Free PMC article.

7

TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1.

Azijn H, Tirry I, Vingerhoets J, de Béthune MP, Kraus G, Boven K, Jochmans D, Van Craenenbroeck E, Picchio G, Rimsky LT. Azijn H, et al. Among authors: jochmans d. Antimicrob Agents Chemother. 2010 Feb;54(2):718-27. doi: 10.1128/AAC.00986-09. Epub 2009 Nov 23. Antimicrob Agents Chemother. 2010. PMID: 19933797 Free PMC article.

8

MAPPIT as a high-throughput screening assay for modulators of protein-protein interactions in HIV and HCV.

Van Schoubroeck B, Van Acker K, Dams G, Jochmans D, Clayton R, Berke JM, Lievens S, Van der Heyden J, Tavernier J. Van Schoubroeck B, et al. Among authors: jochmans d. Methods Mol Biol. 2012;812:295-307. doi: 10.1007/978-1-61779-455-1_18. Methods Mol Biol. 2012. PMID: 22218868

9

Mutations M184V and Y115F in HIV-1 reverse transcriptase discriminate against "nucleotide-competing reverse transcriptase inhibitors".

Ehteshami M, Scarth BJ, Tchesnokov EP, Dash C, Le Grice SF, Hallenberger S, Jochmans D, Götte M. Ehteshami M, et al. Among authors: jochmans d. J Biol Chem. 2008 Oct 31;283(44):29904-11. doi: 10.1074/jbc.M804882200. Epub 2008 Aug 25. J Biol Chem. 2008. PMID: 18728003 Free PMC article.

10

A novel high-throughput cellular screening assay for the discovery of HIV-1 integrase inhibitors.

Van Loock M, Meersseman G, Van Acker K, Van Den Eynde C, Jochmans D, Van Schoubroeck B, Dams G, Heyndrickx L, Clayton RF. Van Loock M, et al. Among authors: jochmans d. J Virol Methods. 2012 Feb;179(2):396-401. doi: 10.1016/j.jviromet.2011.11.029. Epub 2011 Dec 7. J Virol Methods. 2012. PMID: 22172974

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