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Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels.
Shen Q, Feng Q, Wu C, Xiong Q, Tian T, Yuan S, Shi J, Bedwell GJ, Yang R, Aiken C, Engelman AN, Lusk CP, Lin C, Xiong Y. Shen Q, et al. Among authors: bedwell gj. Nat Struct Mol Biol. 2023 Apr;30(4):425-435. doi: 10.1038/s41594-023-00925-9. Epub 2023 Feb 20. Nat Struct Mol Biol. 2023. PMID: 36807645 Free PMC article.
Viral and Host Mediators of Non-Suppressible HIV-1 Viremia.
Mohammadi A, Etemad B, Zhang X, Li Y, Bedwell GJ, Sharaf R, Kittilson A, Melberg M, Wong C, Fajnzylber J, Worrall DP, Rosenthal A, Jordan H, Jilg N, Kaseke C, Giguel F, Lian X, Deo R, Gillespie E, Chishti R, Abrha S, Adams T, Siagian A, Anderson PL, Deeks SG, Lederman MM, Yawetz S, Kuritzkes DR, Lichterfeld MD, Tsibris A, Carrington M, Brumme ZL, Castillo-Mancilla JR, Engelman AN, Gaiha GD, Li JZ. Mohammadi A, et al. Among authors: bedwell gj. medRxiv [Preprint]. 2023 Mar 31:2023.03.30.23287124. doi: 10.1101/2023.03.30.23287124. medRxiv. 2023. Update in: Nat Med. 2023 Dec;29(12):3212-3223. doi: 10.1038/s41591-023-02611-1. PMID: 37034605 Free PMC article. Updated. Preprint.
Viral and host mediators of non-suppressible HIV-1 viremia.
Mohammadi A, Etemad B, Zhang X, Li Y, Bedwell GJ, Sharaf R, Kittilson A, Melberg M, Crain CR, Traunbauer AK, Wong C, Fajnzylber J, Worrall DP, Rosenthal A, Jordan H, Jilg N, Kaseke C, Giguel F, Lian X, Deo R, Gillespie E, Chishti R, Abrha S, Adams T, Siagian A, Dorazio D, Anderson PL, Deeks SG, Lederman MM, Yawetz S, Kuritzkes DR, Lichterfeld MD, Sieg S, Tsibris A, Carrington M, Brumme ZL, Castillo-Mancilla JR, Engelman AN, Gaiha GD, Li JZ. Mohammadi A, et al. Among authors: bedwell gj. Nat Med. 2023 Dec;29(12):3212-3223. doi: 10.1038/s41591-023-02611-1. Epub 2023 Nov 13. Nat Med. 2023. PMID: 37957382 Free PMC article.
HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration.
Jang S, Bedwell GJ, Singh SP, Yu HJ, Arnarson B, Singh PK, Radhakrishnan R, Douglas AW, Ingram ZM, Freniere C, Akkermans O, Sarafianos SG, Ambrose Z, Xiong Y, Anekal PV, Montero Llopis P, KewalRamani VN, Francis AC, Engelman AN. Jang S, et al. Among authors: bedwell gj. Nucleic Acids Res. 2024 Oct 14;52(18):11060-11082. doi: 10.1093/nar/gkae769. Nucleic Acids Res. 2024. PMID: 39258548 Free PMC article.
The role of LEDGF in transcription is exploited by HIV-1 to position integration.
Pathak R, Esnault C, Radhakrishnan R, Singh PK, Zhang H, Dale R, Anand A, Bedwell GJ, Engelman AN, Rabi A, Hormoz S, Singh P, Levin HL. Pathak R, et al. Among authors: bedwell gj. bioRxiv [Preprint]. 2024 Jul 2:2024.06.29.601340. doi: 10.1101/2024.06.29.601340. bioRxiv. 2024. PMID: 39005447 Free PMC article. Preprint.
Determining the Minimum Dataset for Surgical Patients in Africa: A Delphi Study.
Kluyts HL, Bedwell GJ, Bedada AG, Fadalla T, Hewitt-Smith A, Mbwele BA, Mrara B, Omigbodun A, Omoshoro-Jones J, Turton EW, Belachew FK, Chu K, Cloete E, Ekwen G, Elfagieh MA, Elfiky M, Maimbo M, Morais A, Mpirimbanyi C, Munlemvo D, Ndarukwa P, Smalle I, Torborg A, Ulisubisya M, Fawzy M, Gobin V, Mbeki M, Ngumi Z, Patel-Mujajati U, Sama HD, Tumukunde J, Antwi-Kusi A, Basenaro A, Lamacraft G, Madzimbamuto F, Maswime S, Msosa V, Mulwafu W, Youssouf C, Pearse R, Biccard BM. Kluyts HL, et al. Among authors: bedwell gj. World J Surg. 2023 Mar;47(3):581-592. doi: 10.1007/s00268-022-06815-3. Epub 2022 Nov 15. World J Surg. 2023. PMID: 36380103
42 results