Moutinho M - Search Results

1

TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation.

Moutinho M, Coronel I, Tsai AP, Di Prisco GV, Pennington T, Atwood BK, Puntambekar SS, Smith DC, Martinez P, Han S, Lee Y, Lasagna-Reeves CA, Lamb BT, Bissel SJ, Nho K, Landreth GE. Moutinho M, et al. Genome Med. 2023 Feb 20;15(1):11. doi: 10.1186/s13073-023-01160-z. Genome Med. 2023. PMID: 36805764 Free PMC article.

2

Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining.

Palmela I, Sasaki H, Cardoso FL, Moutinho M, Kim KS, Brites D, Brito MA. Palmela I, et al. Among authors: moutinho m. Front Cell Neurosci. 2012 May 10;6:22. doi: 10.3389/fncel.2012.00022. eCollection 2012. Front Cell Neurosci. 2012. PMID: 22590454 Free PMC article.

3

Cholesterol 24-hydroxylase: Brain cholesterol metabolism and beyond.

Moutinho M, Nunes MJ, Rodrigues E. Moutinho M, et al. Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):1911-1920. doi: 10.1016/j.bbalip.2016.09.011. Epub 2016 Sep 20. Biochim Biophys Acta. 2016. PMID: 27663182 Review.

4

Cholesterol 24S-Hydroxylase Overexpression Inhibits the Liver X Receptor (LXR) Pathway by Activating Small Guanosine Triphosphate-Binding Proteins (sGTPases) in Neuronal Cells.

Moutinho M, Nunes MJ, Gomes AQ, Gama MJ, Cedazo-Minguez A, Rodrigues CM, Björkhem I, Rodrigues E. Moutinho M, et al. Mol Neurobiol. 2015;51(3):1489-503. doi: 10.1007/s12035-014-8828-0. Epub 2014 Aug 2. Mol Neurobiol. 2015. PMID: 25084760

5

Neuronal differentiation alters the ratio of Sp transcription factors recruited to the CYP46A1 promoter.

Milagre I, Nunes MJ, Castro-Caldas M, Moutinho M, Gama MJ, Rodrigues E. Milagre I, et al. Among authors: moutinho m. J Neurochem. 2012 Jan;120(2):220-9. doi: 10.1111/j.1471-4159.2011.07577.x. Epub 2011 Nov 28. J Neurochem. 2012. PMID: 22060190 Free article.

6

Marked change in the balance between CYP27A1 and CYP46A1 mediated elimination of cholesterol during differentiation of human neuronal cells.

Milagre I, Olin M, Nunes MJ, Moutinho M, Lövgren-Sandblom A, Gama MJ, Björkhem I, Rodrigues E. Milagre I, et al. Among authors: moutinho m. Neurochem Int. 2012 Jan;60(2):192-8. doi: 10.1016/j.neuint.2011.12.003. Epub 2011 Dec 13. Neurochem Int. 2012. PMID: 22185844

7

Okadaic acid inhibits the trichostatin A-mediated increase of human CYP46A1 neuronal expression in a ERK1/2-Sp3-dependent pathway.

Nunes MJ, Moutinho M, Milagre I, Gama MJ, Rodrigues E. Nunes MJ, et al. Among authors: moutinho m. J Lipid Res. 2012 Sep;53(9):1910-9. doi: 10.1194/jlr.M027680. Epub 2012 Jun 12. J Lipid Res. 2012. PMID: 22693257 Free PMC article.

8

Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk.

Moutinho M, Nunes MJ, Correia JC, Gama MJ, Castro-Caldas M, Cedazo-Minguez A, Rodrigues CM, Björkhem I, Ruas JL, Rodrigues E. Moutinho M, et al. Sci Rep. 2016 Aug 5;6:30928. doi: 10.1038/srep30928. Sci Rep. 2016. PMID: 27491694 Free PMC article.

9

Therapeutic potential of nuclear receptor agonists in Alzheimer's disease.

Moutinho M, Landreth GE. Moutinho M, et al. J Lipid Res. 2017 Oct;58(10):1937-1949. doi: 10.1194/jlr.R075556. Epub 2017 Mar 6. J Lipid Res. 2017. PMID: 28264880 Free PMC article. Review.

10

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.

Cheng-Hathaway PJ, Reed-Geaghan EG, Jay TR, Casali BT, Bemiller SM, Puntambekar SS, von Saucken VE, Williams RY, Karlo JC, Moutinho M, Xu G, Ransohoff RM, Lamb BT, Landreth GE. Cheng-Hathaway PJ, et al. Among authors: moutinho m. Mol Neurodegener. 2018 Jun 1;13(1):29. doi: 10.1186/s13024-018-0262-8. Mol Neurodegener. 2018. PMID: 29859094 Free PMC article.

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