Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice.
Wang Y, Shilagardi K, Hsu T, Odinammadu KO, Maruyama T, Wu W, Lin CS, Damoci CB, Spear ED, Shin JY, Hsu W, Michaelis S, Worman HJ.
Wang Y, et al. Among authors: maruyama t.
Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2118695119. doi: 10.1073/pnas.2118695119.
Proc Natl Acad Sci U S A. 2022.
PMID: 35197292
Free PMC article.