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A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.
Altea-Manzano P, Doglioni G, Liu Y, Cuadros AM, Nolan E, Fernández-García J, Wu Q, Planque M, Laue KJ, Cidre-Aranaz F, Liu XZ, Marin-Bejar O, Van Elsen J, Vermeire I, Broekaert D, Demeyer S, Spotbeen X, Idkowiak J, Montagne A, Demicco M, Alkan HF, Rabas N, Riera-Domingo C, Richard F, Geukens T, De Schepper M, Leduc S, Hatse S, Lambrechts Y, Kay EJ, Lilla S, Alekseenko A, Geldhof V, Boeckx B, de la Calle Arregui C, Floris G, Swinnen JV, Marine JC, Lambrechts D, Pelechano V, Mazzone M, Zanivan S, Cools J, Wildiers H, Baud V, Grünewald TGP, Ben-David U, Desmedt C, Malanchi I, Fendt SM. Altea-Manzano P, et al. Among authors: pelechano v. Nat Cancer. 2023 Mar;4(3):344-364. doi: 10.1038/s43018-023-00513-2. Epub 2023 Feb 2. Nat Cancer. 2023. PMID: 36732635 Free PMC article.
The association of the RSC remodeler complex with chromatin is influenced by the prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae.
Cuevas-Bermúdez A, Martínez-Fernández V, Garrido-Godino AI, Jordán-Pla A, Peñate X, Martín-Expósito M, Gutiérrez G, Govind CK, Chávez S, Pelechano V, Navarro F. Cuevas-Bermúdez A, et al. Among authors: pelechano v. Biochim Biophys Acta Gene Regul Mech. 2024 Mar;1867(1):194995. doi: 10.1016/j.bbagrm.2023.194995. Epub 2023 Nov 13. Biochim Biophys Acta Gene Regul Mech. 2024. PMID: 37967810
A global genetic interaction network maps a wiring diagram of cellular function.
Costanzo M, VanderSluis B, Koch EN, Baryshnikova A, Pons C, Tan G, Wang W, Usaj M, Hanchard J, Lee SD, Pelechano V, Styles EB, Billmann M, van Leeuwen J, van Dyk N, Lin ZY, Kuzmin E, Nelson J, Piotrowski JS, Srikumar T, Bahr S, Chen Y, Deshpande R, Kurat CF, Li SC, Li Z, Usaj MM, Okada H, Pascoe N, San Luis BJ, Sharifpoor S, Shuteriqi E, Simpkins SW, Snider J, Suresh HG, Tan Y, Zhu H, Malod-Dognin N, Janjic V, Przulj N, Troyanskaya OG, Stagljar I, Xia T, Ohya Y, Gingras AC, Raught B, Boutros M, Steinmetz LM, Moore CL, Rosebrock AP, Caudy AA, Myers CL, Andrews B, Boone C. Costanzo M, et al. Among authors: pelechano v. Science. 2016 Sep 23;353(6306):aaf1420. doi: 10.1126/science.aaf1420. Science. 2016. PMID: 27708008 Free PMC article.
The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons.
García-Martínez J, Delgado-Ramos L, Ayala G, Pelechano V, Medina DA, Carrasco F, González R, Andrés-León E, Steinmetz L, Warringer J, Chávez S, Pérez-Ortín JE. García-Martínez J, et al. Among authors: pelechano v. Nucleic Acids Res. 2016 May 5;44(8):3643-58. doi: 10.1093/nar/gkv1512. Epub 2015 Dec 29. Nucleic Acids Res. 2016. PMID: 26717982 Free PMC article.
Recommendations for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples.
Kubik S, Marques AC, Xing X, Silvery J, Bertelli C, De Maio F, Pournaras S, Burr T, Duffourd Y, Siemens H, Alloui C, Song L, Wenger Y, Saitta A, Macheret M, Smith EW, Menu P, Brayer M, Steinmetz LM, Si-Mohammed A, Chuisseu J, Stevens R, Constantoulakis P, Sali M, Greub G, Tiemann C, Pelechano V, Willig A, Xu Z. Kubik S, et al. Among authors: pelechano v. Clin Microbiol Infect. 2021 Jul;27(7):1036.e1-1036.e8. doi: 10.1016/j.cmi.2021.03.029. Epub 2021 Apr 2. Clin Microbiol Infect. 2021. PMID: 33813118 Free PMC article.
82 results