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Page 1
Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects.
Blömeke L, Rehn F, Pils M, Kraemer-Schulien V, Cousin A, Kutzsche J, Bujnicki T, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Rostamzadeh A, Düzel E, Glanz W, Incesoy EI, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Munk MH, Spottke A, Roy N, Heneka MT, Brosseron F, Wagner M, Roeske S, Ramirez A, Schmid M, Jessen F, Bannach O, Peters O, Willbold D. Blömeke L, et al. Commun Med (Lond). 2024 Dec 10;4(1):262. doi: 10.1038/s43856-024-00690-w. Commun Med (Lond). 2024. PMID: 39658587 Free article.
Elevated Aβ aggregates in feces from Alzheimer's disease patients: a proof-of-concept study.
Pils M, Dybala A, Schaffrath A, Rehn F, Kutzsche J, Blömeke L, Tusche M, Özdüzenciler P, Bujnicki T, Kraemer-Schulien V, Gramespacher H, Schmieschek MHT, Barbe MT, Onur OA, Fink GR, Tamgüney G, Bannach O, Willbold D. Pils M, et al. Among authors: blomeke l. Alzheimers Res Ther. 2024 Oct 14;16(1):223. doi: 10.1186/s13195-024-01597-3. Alzheimers Res Ther. 2024. PMID: 39402637 Free PMC article.
Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology.
Blömeke L, Rehn F, Kraemer-Schulien V, Kutzsche J, Pils M, Bujnicki T, Lewczuk P, Kornhuber J, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Lohse A, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Rostamzadeh A, Düzel E, Glanz W, Incesoy EI, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Sanzenbacher C, Spottke A, Roy-Kluth N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Kleineidam L, Stark M, Schmid M, Jessen F, Bannach O, Willbold D, Peters O. Blömeke L, et al. Alzheimers Dement (Amst). 2024 Apr 25;16(2):e12589. doi: 10.1002/dad2.12589. eCollection 2024 Apr-Jun. Alzheimers Dement (Amst). 2024. PMID: 38666085 Free PMC article.
Oral treatment with the all-d-peptide RD2 enhances cognition in aged beagle dogs - A model of sporadic Alzheimer's disease.
Kutzsche J, Schemmert S, Bujnicki T, Zafiu C, Halbgebauer S, Kraemer-Schulien V, Pils M, Blömeke L, Post J, Kulawik A, Jürgens D, Rossberg WM, Hümpel M, Bannach O, Otto M, Araujo JA, Willuweit A, Willbold D. Kutzsche J, et al. Among authors: blomeke l. Heliyon. 2023 Jul 29;9(8):e18443. doi: 10.1016/j.heliyon.2023.e18443. eCollection 2023 Aug. Heliyon. 2023. PMID: 37609390 Free PMC article.
Tau protein aggregation associated with SARS-CoV-2 main protease.
Eberle RJ, Coronado MA, Gering I, Sommerhage S, Korostov K, Stefanski A, Stühler K, Kraemer-Schulien V, Blömeke L, Bannach O, Willbold D. Eberle RJ, et al. Among authors: blomeke l. PLoS One. 2023 Aug 21;18(8):e0288138. doi: 10.1371/journal.pone.0288138. eCollection 2023. PLoS One. 2023. PMID: 37603556 Free PMC article.
Patients with isolated REM-sleep behavior disorder have elevated levels of alpha-synuclein aggregates in stool.
Schaffrath A, Schleyken S, Seger A, Jergas H, Özdüzenciler P, Pils M, Blömeke L, Cousin A, Willbold J, Bujnicki T, Bannach O, Fink GR, Willbold D, Sommerauer M, Barbe MT, Tamgüney G. Schaffrath A, et al. Among authors: blomeke l. NPJ Parkinsons Dis. 2023 Feb 2;9(1):14. doi: 10.1038/s41531-023-00458-4. NPJ Parkinsons Dis. 2023. PMID: 36732520 Free PMC article.
Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting.
Blömeke L, Pils M, Kraemer-Schulien V, Dybala A, Schaffrath A, Kulawik A, Rehn F, Cousin A, Nischwitz V, Willbold J, Zack R, Tropea TF, Bujnicki T, Tamgüney G, Weintraub D, Irwin D, Grossman M, Wolk DA, Trojanowski JQ, Bannach O, Chen-Plotkin A, Willbold D. Blömeke L, et al. NPJ Parkinsons Dis. 2022 Jun 2;8(1):68. doi: 10.1038/s41531-022-00330-x. NPJ Parkinsons Dis. 2022. PMID: 35655068 Free PMC article.