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Page 1
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer RE, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, Mulkearns-Hubert EE, Johnson S, Alvarado J, Rich JN, Holland EC, Paddison PJ, Patel AP, Stauffer SR, Hubert CG, Lathia JD. Mitchell K, et al. Among authors: silver dj. Genes Dev. 2023 Feb 1;37(3-4):86-102. doi: 10.1101/gad.349803.122. Epub 2023 Feb 2. Genes Dev. 2023. PMID: 36732025 Free PMC article.
Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling.
Alvarado AG, Turaga SM, Sathyan P, Mulkearns-Hubert EE, Otvos B, Silver DJ, Hale JS, Flavahan WA, Zinn PO, Sinyuk M, Li M, Guda MR, Velpula KK, Tsung AJ, Nakano I, Vogelbaum MA, Majumder S, Rich JN, Lathia JD. Alvarado AG, et al. Among authors: silver dj. Neuro Oncol. 2016 May;18(5):656-66. doi: 10.1093/neuonc/nov196. Epub 2015 Sep 15. Neuro Oncol. 2016. PMID: 26374689 Free PMC article.
Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models.
Dermawan JK, Hitomi M, Silver DJ, Wu Q, Sandlesh P, Sloan AE, Purmal AA, Gurova KV, Rich JN, Lathia JD, Stark GR, Venere M. Dermawan JK, et al. Among authors: silver dj. Cancer Res. 2016 Apr 15;76(8):2432-42. doi: 10.1158/0008-5472.CAN-15-2162. Epub 2016 Feb 26. Cancer Res. 2016. PMID: 26921329 Free PMC article.
Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion.
Otvos B, Silver DJ, Mulkearns-Hubert EE, Alvarado AG, Turaga SM, Sorensen MD, Rayman P, Flavahan WA, Hale JS, Stoltz K, Sinyuk M, Wu Q, Jarrar A, Kim SH, Fox PL, Nakano I, Rich JN, Ransohoff RM, Finke J, Kristensen BW, Vogelbaum MA, Lathia JD. Otvos B, et al. Among authors: silver dj. Stem Cells. 2016 Aug;34(8):2026-39. doi: 10.1002/stem.2393. Epub 2016 May 27. Stem Cells. 2016. PMID: 27145382 Free PMC article.
Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression.
Alvarado AG, Thiagarajan PS, Mulkearns-Hubert EE, Silver DJ, Hale JS, Alban TJ, Turaga SM, Jarrar A, Reizes O, Longworth MS, Vogelbaum MA, Lathia JD. Alvarado AG, et al. Among authors: silver dj. Cell Stem Cell. 2017 Apr 6;20(4):450-461.e4. doi: 10.1016/j.stem.2016.12.001. Epub 2017 Jan 12. Cell Stem Cell. 2017. PMID: 28089910 Free PMC article.
New Advances and Challenges of Targeting Cancer Stem Cells.
Dashzeveg NK, Taftaf R, Ramos EK, Torre-Healy L, Chumakova A, Silver DJ, Alban TJ, Sinyuk M, Thiagarajan PS, Jarrar AM, Turaga SM, Saygin C, Mulkearns-Hubert E, Hitomi M, Rich JN, Gerson SL, Lathia JD, Liu H. Dashzeveg NK, et al. Among authors: silver dj. Cancer Res. 2017 Oct 1;77(19):5222-5227. doi: 10.1158/0008-5472.CAN-17-0054. Epub 2017 Sep 19. Cancer Res. 2017. PMID: 28928129 Free PMC article.
Development of a Cx46 Targeting Strategy for Cancer Stem Cells.
Mulkearns-Hubert EE, Torre-Healy LA, Silver DJ, Eurich JT, Bayik D, Serbinowski E, Hitomi M, Zhou J, Przychodzen B, Zhang R, Sprowls SA, Hale JS, Alban TJ, Berezovsky A, Bell BA, Lockman PR, Jha BK, Lathia JD. Mulkearns-Hubert EE, et al. Among authors: silver dj. Cell Rep. 2019 Apr 23;27(4):1062-1072.e5. doi: 10.1016/j.celrep.2019.03.079. Cell Rep. 2019. PMID: 31018124 Free PMC article.
52 results