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266 results

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Page 1
Extremely potent pan-sarbecovirus neutralizing antibodies generated by immunization of macaques with an AS03-adjuvanted monovalent subunit vaccine against SARS-CoV-2.
Feng Y, Yuan M, Powers JM, Hu M, Munt JE, Arunachalam PS, Leist SR, Bellusci L, Adams LE, Sundaramurthy S, Shirreff LM, Mallory ML, Scooby TD, Moreno A, O'Hagan DT, Kleanthous H, Villinger FJ, Veesler D, King NP, Suthar MS, Khurana S, Baric RS, Wilson IA, Pulendran B. Feng Y, et al. Among authors: pulendran b. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524784. doi: 10.1101/2023.01.19.524784. bioRxiv. 2023. PMID: 36711543 Free PMC article. Preprint.
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.
Walls AC, Miranda MC, Pham MN, Schäfer A, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O'Connor MA, Shireff L, Ferrell DE, Brunette N, Kepl E, Bowen J, Zepeda SK, Starr T, Hsieh CL, Fiala B, Wrenn S, Pettie D, Sydeman C, Johnson M, Blackstone A, Ravichandran R, Ogohara C, Carter L, Tilles SW, Rappuoli R, O'Hagan DT, Van Der Most R, Van Voorhis WC, McLellan JS, Kleanthous H, Sheahan TP, Fuller DH, Villinger F, Bloom J, Pulendran B, Baric R, King N, Veesler D. Walls AC, et al. Among authors: pulendran b. bioRxiv [Preprint]. 2021 Mar 16:2021.03.15.435528. doi: 10.1101/2021.03.15.435528. bioRxiv. 2021. Update in: Cell. 2021 Oct 14;184(21):5432-5447.e16. doi: 10.1016/j.cell.2021.09.015 PMID: 33758839 Free PMC article. Updated. Preprint.
Hydrogel-based slow release of a receptor-binding domain subunit vaccine elicits neutralizing antibody responses against SARS-CoV-2.
Gale EC, Powell AE, Roth GA, Meany EL, Yan J, Ou BS, Grosskopf AK, Adamska J, Picece VCTM, Dâ Aquino AI, Pulendran B, Kim PS, Appel EA. Gale EC, et al. Among authors: pulendran b. bioRxiv [Preprint]. 2021 Aug 29:2021.03.31.437792. doi: 10.1101/2021.03.31.437792. bioRxiv. 2021. Update in: Adv Mater. 2021 Dec;33(51):e2104362. doi: 10.1002/adma.202104362 PMID: 33821276 Free PMC article. Updated. Preprint.
mRNA vaccination compared to infection elicits an IgG-predominant response with greater SARS-CoV-2 specificity and similar decrease in variant spike recognition.
Röltgen K, Nielsen SCA, Arunachalam PS, Yang F, Hoh RA, Wirz OF, Lee AS, Gao F, Mallajosyula V, Li C, Haraguchi E, Shoura MJ, Wilbur JL, Wohlstadter JN, Davis MM, Pinsky BA, Sigal GB, Pulendran B, Nadeau KC, Boyd SD. Röltgen K, et al. Among authors: pulendran b. medRxiv [Preprint]. 2021 Apr 7:2021.04.05.21254952. doi: 10.1101/2021.04.05.21254952. medRxiv. 2021. PMID: 33851181 Free PMC article. Preprint.
Systems biological assessment of human immunity to BNT162b2 mRNA vaccination.
Arunachalam PS, Scott MKD, Hagan T, Li C, Feng Y, Wimmers F, Grigoryan L, Trisal M, Edara VV, Lai L, Chang SE, Feng A, Dhingra S, Shah M, Lee AS, Chinthrajah S, Sindher T, Mallajosyula V, Gao F, Sigal N, Kowli S, Gupta S, Pellegrini K, Tharp G, Maysel-Auslender S, Bosinger S, Maecker HT, Boyd SD, Davis MM, Utz PJ, Suthar MS, Khatri P, Nadeau KC, Pulendran B. Arunachalam PS, et al. Among authors: pulendran b. Res Sq [Preprint]. 2021 Apr 22:rs.3.rs-438662. doi: 10.21203/rs.3.rs-438662/v1. Res Sq. 2021. Update in: Nature. 2021 Aug;596(7872):410-416. doi: 10.1038/s41586-021-03791-x PMID: 34013244 Free PMC article. Updated. Preprint.
Structurally and functionally distinct early antibody responses predict COVID-19 disease trajectory and mRNA vaccine response.
Chakraborty S, Gonzalez JC, Sievers BL, Mallajosyula V, Chakraborty S, Dubey M, Ashraf U, Cheng BY, Kathale N, Tran KQT, Scallan C, Sinnott A, Cassidy A, Chen ST, Gelbart T, Gao F, Golan Y, Ji X, Kim-Schulze S, Prahl M, Gaw SL, Gnjatic S, Marron TU, Merad M, Arunachalam PS, Boyd SD, Davis MM, Holubar M, Khosla C, Maecker HT, Maldonado Y, Mellins ED, Nadeau KC, Pulendran B, Singh U, Subramanian A, Utz PJ, Sherwood R, Zhang S, Jagannathan P, Tan GS, Wang TT. Chakraborty S, et al. Among authors: pulendran b. bioRxiv [Preprint]. 2021 Dec 27:2021.05.25.445649. doi: 10.1101/2021.05.25.445649. bioRxiv. 2021. PMID: 34075376 Free PMC article. Preprint.
Durability of immune responses to the booster mRNA vaccination against COVID-19.
Arunachalam PS, Lai L, Samaha H, Feng Y, Hu M, Hui HS, Wali B, Ellis M, Huerta C, Bechnack K, Bechnack S, Lee M, Litvack M, Losada C, Grifoni A, Sette A, Zarnitsyna VI, Rouphael N, Suthar MS, Pulendran B. Arunachalam PS, et al. Among authors: pulendran b. medRxiv [Preprint]. 2022 Dec 4:2022.12.02.22282921. doi: 10.1101/2022.12.02.22282921. medRxiv. 2022. Update in: J Clin Invest. 2023 May 15;133(10):e167955. doi: 10.1172/JCI167955 PMID: 36482977 Free PMC article. Updated. Preprint.
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates.
Weidenbacher PA, Sanyal M, Friedland N, Tang S, Arunachalam PS, Hu M, Kumru OS, Morris MK, Fontenot J, Shirreff L, Do J, Cheng YC, Vasudevan G, Feinberg MB, Villinger FJ, Hanson C, Joshi SB, Volkin DB, Pulendran B, Kim PS. Weidenbacher PA, et al. Among authors: pulendran b. bioRxiv [Preprint]. 2022 Dec 26:2022.12.25.521784. doi: 10.1101/2022.12.25.521784. bioRxiv. 2022. Update in: Nat Commun. 2023 Apr 17;14(1):2149. doi: 10.1038/s41467-023-37417-9 PMID: 36597527 Free PMC article. Updated. Preprint.
Systems biological assessment of the temporal dynamics of immunity to a viral infection in the first weeks and months of life.
Wimmers F, Burrell AR, Feng Y, Zheng H, Arunachalam PS, Hu M, Spranger S, Nyhoff L, Joshi D, Trisal M, Awasthi M, Bellusci L, Ashraf U, Kowli S, Konvinse KC, Yang E, Blanco M, Pellegrini K, Tharp G, Hagan T, Chinthrajah RS, Grifoni A, Sette A, Nadeau KC, Haslam DB, Bosinger SE, Wrammert J, Maecker HT, Utz PJ, Wang TT, Khurana S, Khatri P, Staat MA, Pulendran B. Wimmers F, et al. Among authors: pulendran b. medRxiv [Preprint]. 2023 Jan 31:2023.01.28.23285133. doi: 10.1101/2023.01.28.23285133. medRxiv. 2023. PMID: 36778389 Free PMC article. Preprint.
Saponin Nanoparticle Adjuvants Incorporating Toll-Like Receptor Agonists Drive Distinct Immune Signatures and Potent Vaccine Responses.
Ou BS, Baillet J, Filsinger Interrante MV, Adamska JZ, Zhou X, Saouaf OM, Yan J, Klich JH, Jons CK, Meany EL, Valdez AS, Carter L, Pulendran B, King NP, Appel EA. Ou BS, et al. Among authors: pulendran b. bioRxiv [Preprint]. 2024 Jun 27:2023.07.16.549249. doi: 10.1101/2023.07.16.549249. bioRxiv. 2024. Update in: Sci Adv. 2024 Aug 9;10(32):eadn7187. doi: 10.1126/sciadv.adn7187 PMID: 37577608 Free PMC article. Updated. Preprint.
266 results