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Cross center single-cell RNA sequencing study of the immune microenvironment in rapid progressing multiple myeloma.
Pilcher W, Thomas BE, Bhasin SS, Jayasinghe RG, Yao L, Gonzalez-Kozlova E, Dasari S, Kim-Schulze S, Rahman A, Patton J, Fiala M, Cheloni G, Kourelis T, Dhodapkar MV, Vij R, Mehr S, Hamilton M, Cho HJ, Auclair D, Avigan DE, Kumar SK, Gnjatic S, Ding L, Bhasin M. Pilcher W, et al. Among authors: jayasinghe rg. NPJ Genom Med. 2023 Jan 26;8(1):3. doi: 10.1038/s41525-022-00340-x. NPJ Genom Med. 2023. PMID: 36702834 Free PMC article.
Co-evolution of tumor and immune cells during progression of multiple myeloma.
Liu R, Gao Q, Foltz SM, Fowles JS, Yao L, Wang JT, Cao S, Sun H, Wendl MC, Sethuraman S, Weerasinghe A, Rettig MP, Storrs EP, Yoon CJ, Wyczalkowski MA, McMichael JF, Kohnen DR, King J, Goldsmith SR, O'Neal J, Fulton RS, Fronick CC, Ley TJ, Jayasinghe RG, Fiala MA, Oh ST, DiPersio JF, Vij R, Ding L. Liu R, et al. Among authors: jayasinghe rg. Nat Commun. 2021 May 7;12(1):2559. doi: 10.1038/s41467-021-22804-x. Nat Commun. 2021. PMID: 33963182 Free PMC article.
CS1 CAR-T targeting the distal domain of CS1 (SLAMF7) shows efficacy in high tumor burden myeloma model despite fratricide of CD8+CS1 expressing CAR-T cells.
O'Neal J, Ritchey JK, Cooper ML, Niswonger J, Sofía González L, Street E, Rettig MP, Gladney SW, Gehrs L, Abboud R, Prior JL, Haas GJ, Jayasinghe RG, Ding L, Ghobadi A, Vij R, DiPersio JF. O'Neal J, et al. Among authors: jayasinghe rg. Leukemia. 2022 Jun;36(6):1625-1634. doi: 10.1038/s41375-022-01559-4. Epub 2022 Apr 14. Leukemia. 2022. PMID: 35422095 Free PMC article.
Pollock: fishing for cell states.
Storrs EP, Zhou DC, Wendl MC, Wyczalkowski MA, Karpova A, Wang LB, Li Y, Southard-Smith A, Jayasinghe RG, Yao L, Liu R, Wu Y, Terekhanova NV, Zhu H, Herndon JM, Puram S, Chen F, Gillanders WE, Fields RC, Ding L. Storrs EP, et al. Among authors: jayasinghe rg. Bioinform Adv. 2022 May 13;2(1):vbac028. doi: 10.1093/bioadv/vbac028. eCollection 2022. Bioinform Adv. 2022. PMID: 35603231 Free PMC article.
Single-Cell Discovery and Multiomic Characterization of Therapeutic Targets in Multiple Myeloma.
Yao L, Wang JT, Jayasinghe RG, O'Neal J, Tsai CF, Rettig MP, Song Y, Liu R, Zhao Y, Ibrahim OM, Fiala MA, Fortier JM, Chen S, Gehrs L, Rodrigues FM, Wendl MC, Kohnen D, Shinkle A, Cao S, Foltz SM, Zhou DC, Storrs E, Wyczalkowski MA, Mani S, Goldsmith SR, Zhu Y, Hamilton M, Liu T, Chen F, Vij R, Ding L, DiPersio JF. Yao L, et al. Among authors: jayasinghe rg. Cancer Res. 2023 Apr 14;83(8):1214-1233. doi: 10.1158/0008-5472.CAN-22-1769. Cancer Res. 2023. PMID: 36779841 Free PMC article.
Comprehensive Characterization of the Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis.
Yao L, Jayasinghe RG, Lee BH, Bhasin SS, Pilcher W, Doxie DB, Gonzalez-Kozlova E, Dasari S, Fiala MA, Pita-Juarez Y, Strausbauch M, Kelly G, Thomas BE, Kumar SK, Cho HJ, Anderson E, Wendl MC, Dawson T, D'souza D, Oh ST, Cheloni G, Li Y, DiPersio JF, Rahman AH, Dhodapkar KM, Kim-Schulze S, Vij R, Vlachos IS, Mehr S, Hamilton M, Auclair D, Kourelis T, Avigan D, Dhodapkar MV, Gnjatic S, Bhasin MK, Ding L. Yao L, et al. Among authors: jayasinghe rg. Cancer Res Commun. 2022 Oct 25;2(10):1255-1265. doi: 10.1158/2767-9764.CRC-22-0022. eCollection 2022 Oct. Cancer Res Commun. 2022. PMID: 36969740 Free PMC article.
Somatic mutation phasing and haplotype extension using linked-reads in multiple myeloma.
Foltz SM, Li Y, Yao L, Terekhanova NV, Weerasinghe A, Gao Q, Dong G, Schindler M, Cao S, Sun H, Jayasinghe RG, Fulton RS, Fronick CC, King J, Kohnen DR, Fiala MA, Chen K, DiPersio JF, Vij R, Ding L. Foltz SM, et al. Among authors: jayasinghe rg. bioRxiv [Preprint]. 2024 Aug 10:2024.08.09.607342. doi: 10.1101/2024.08.09.607342. bioRxiv. 2024. PMID: 39149342 Free PMC article. Preprint.
LINC01432 binds to CELF2 in newly diagnosed multiple myeloma promoting short progression-free survival to standard therapy.
Mishra R, Thunuguntla P, Perkin A, Duraiyan D, Bagwill K, Gonzales S, Brizuela V, Daly S, Chang YJ, Abebe M, Rajana Y, Wichmann K, Bolick C, King J, Fiala M, Fortier J, Jayasinghe R, Schroeder M, Ding L, Vij R, Silva-Fisher J. Mishra R, et al. Res Sq [Preprint]. 2024 Oct 15:rs.3.rs-4888379. doi: 10.21203/rs.3.rs-4888379/v1. Res Sq. 2024. PMID: 39483883 Free PMC article. Preprint.
97 results