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Successful lung transplantation using an allograft from a COVID-19-recovered donor: a potential role for subgenomic RNA to guide organ utilization.
Saharia KK, Ramelli SC, Stein SR, Roder AE, Kreitman A, Banakis S, Chung JY, Burbelo PD, Singh M, Reed RM, Patel V, Rabin J, Krupnick AS, Cohen JI, de Wit E, Ghedin E, Hewitt SM, Vannella KM, Chertow DS, Grazioli A. Saharia KK, et al. Among authors: de wit e. Am J Transplant. 2023 Jan;23(1):101-107. doi: 10.1016/j.ajt.2022.09.001. Epub 2023 Jan 11. Am J Transplant. 2023. PMID: 36695611 Free PMC article.
Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys.
Speranza E, Williamson BN, Feldmann F, Sturdevant GL, Pérez-Pérez L, Meade-White K, Smith BJ, Lovaglio J, Martens C, Munster VJ, Okumura A, Shaia C, Feldmann H, Best SM, de Wit E. Speranza E, et al. Among authors: de wit e. Sci Transl Med. 2021 Jan 27;13(578):eabe8146. doi: 10.1126/scitranslmed.abe8146. Epub 2021 Jan 11. Sci Transl Med. 2021. PMID: 33431511 Free PMC article.
K18-hACE2 mice develop respiratory disease resembling severe COVID-19.
Yinda CK, Port JR, Bushmaker T, Offei Owusu I, Purushotham JN, Avanzato VA, Fischer RJ, Schulz JE, Holbrook MG, Hebner MJ, Rosenke R, Thomas T, Marzi A, Best SM, de Wit E, Shaia C, van Doremalen N, Munster VJ. Yinda CK, et al. Among authors: de wit e. PLoS Pathog. 2021 Jan 19;17(1):e1009195. doi: 10.1371/journal.ppat.1009195. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33465158 Free PMC article.
Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome.
Sulaiman I, Chung M, Angel L, Tsay JJ, Wu BG, Yeung ST, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal SA, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Pérez-Pérez L, Shen G, Jour G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman DH, Weiden M, Heguy A, Evans L, Uyeki TM, Clemente JC, de Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst CV, Koide S, Stapleford KA, Khanna KM, Ghedin E, Segal LN. Sulaiman I, et al. Among authors: de wit e. Nat Microbiol. 2021 Oct;6(10):1245-1258. doi: 10.1038/s41564-021-00961-5. Epub 2021 Aug 31. Nat Microbiol. 2021. PMID: 34465900 Free PMC article.
Year-long COVID-19 infection reveals within-host evolution of SARS-CoV-2 in a patient with B cell depletion.
Nussenblatt V, Roder AE, Das S, de Wit E, Youn JH, Banakis S, Mushegian A, Mederos C, Wang W, Chung M, Pérez-Pérez L, Palmore T, Brudno JN, Kochenderfer JN, Ghedin E. Nussenblatt V, et al. Among authors: de wit e. medRxiv [Preprint]. 2021 Oct 5:2021.10.02.21264267. doi: 10.1101/2021.10.02.21264267. medRxiv. 2021. Update in: J Infect Dis. 2022 Apr 1;225(7):1118-1123. doi: 10.1093/infdis/jiab622 PMID: 34642697 Free PMC article. Updated. Preprint.
Subcutaneous remdesivir administration prevents interstitial pneumonia in rhesus macaques inoculated with SARS-CoV-2.
Williamson BN, Pérez-Pérez L, Schwarz B, Feldmann F, Holbrook MG, Singh M, Lye DS, Babusis D, Subramanian R, Haddock E, Okumura A, Hanley PW, Lovaglio J, Bosio CM, Porter DP, Cihlar T, Mackman RL, Saturday G, de Wit E. Williamson BN, et al. Among authors: de wit e. Antiviral Res. 2022 Feb;198:105246. doi: 10.1016/j.antiviral.2022.105246. Epub 2022 Jan 13. Antiviral Res. 2022. PMID: 35032523 Free PMC article.
Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques.
Speranza E, Purushotham JN, Port JR, Schwarz B, Flagg M, Williamson BN, Feldmann F, Singh M, Pérez-Pérez L, Sturdevant GL, Roberts LM, Carmody A, Schulz JE, van Doremalen N, Okumura A, Lovaglio J, Hanley PW, Shaia C, Germain RN, Best SM, Munster VJ, Bosio CM, de Wit E. Speranza E, et al. Among authors: de wit e. Life Sci Alliance. 2022 Jan 17;5(4):e202101314. doi: 10.26508/lsa.202101314. Print 2022 Apr. Life Sci Alliance. 2022. PMID: 35039442 Free PMC article.
320 results