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Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Alzheimer's disease and frontotemporal dementia.
Ji M, Xie XX, Liu DQ, Yu XL, Zhang Y, Zhang LX, Wang SW, Huang YR, Liu RT. Ji M, et al. Among authors: liu rt, liu dq. Alzheimers Res Ther. 2018 Jun 19;10(1):55. doi: 10.1186/s13195-018-0378-7. Alzheimers Res Ther. 2018. PMID: 29914543 Free PMC article.
Multifunctional Superparamagnetic Iron Oxide Nanoparticles Conjugated with Aβ Oligomer-Specific scFv Antibody and Class A Scavenger Receptor Activator Show Early Diagnostic Potentials for Alzheimer's Disease.
Liu XG, Zhang L, Lu S, Liu DQ, Zhang LX, Yu XL, Liu RT. Liu XG, et al. Among authors: liu rt, liu dq. Int J Nanomedicine. 2020 Jul 10;15:4919-4932. doi: 10.2147/IJN.S240953. eCollection 2020. Int J Nanomedicine. 2020. PMID: 32764925 Free PMC article.
A mimotope of Aβ oligomers may also behave as a β-sheet inhibitor.
Zhang YX, Wang SW, Lu S, Zhang LX, Liu DQ, Ji M, Wang WY, Liu RT. Zhang YX, et al. Among authors: liu rt, liu dq. FEBS Lett. 2017 Nov;591(21):3615-3624. doi: 10.1002/1873-3468.12871. Epub 2017 Oct 13. FEBS Lett. 2017. PMID: 28976547 Free article.
306 results