Cao R - Search Results

1

Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases.

Chen Y, Chen L, Xu H, Cao R, Morisseau C, Zhang M, Shi Y, Hammock BD, Wang J, Zhuang J, Liu Z, Chen G. Chen Y, et al. Among authors: cao r. J Med Chem. 2023 Feb 23;66(4):2979-3009. doi: 10.1021/acs.jmedchem.2c01996. Epub 2023 Jan 23. J Med Chem. 2023. PMID: 36689364 Free PMC article.

2

Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment of neuropathic pain.

Du F, Cao R, Chen L, Sun J, Shi Y, Fu Y, Hammock BD, Zheng Z, Liu Z, Chen G. Du F, et al. Among authors: cao r. Acta Pharm Sin B. 2022 Mar;12(3):1377-1389. doi: 10.1016/j.apsb.2021.09.018. Epub 2021 Sep 22. Acta Pharm Sin B. 2022. PMID: 35530144 Free PMC article.

3

The bexarotene derivative OAB-14 ameliorates cognitive decline in APP/PS1 transgenic mice by suppressing microglia-mediated neuroinflammation through the PPAR-γ pathway.

Zhang F, Cao RL, Liu P, Chi TY, Ji XF, Zheng ZH, Chen GL, Zou LB. Zhang F, et al. Int Immunopharmacol. 2023 Nov;124(Pt A):110911. doi: 10.1016/j.intimp.2023.110911. Epub 2023 Sep 9. Int Immunopharmacol. 2023. PMID: 37696142

4

Synthesis and biological evaluations of 8-biaryl-2,2-dimethylbenzopyranamide derivatives against Alzheimer's disease and ischemic stroke.

Cao R, Du F, Cui Y, Qi M, Zhuang J, Wang J, Zhang M, Zhang X, Liu Z, Zou L, Xiao W, Chen G. Cao R, et al. Bioorg Chem. 2024 Feb;143:107064. doi: 10.1016/j.bioorg.2023.107064. Epub 2023 Dec 25. Bioorg Chem. 2024. PMID: 38150937

5

Design and Synthesis of Dual-Targeting Inhibitors of sEH and HDAC6 for the Treatment of Neuropathic Pain and Lipopolysaccharide-Induced Mortality.

Chen Y, Sun J, Tong H, Wang J, Cao R, Xu H, Chen L, Morisseau C, Zhang M, Shi Y, Han C, Zhuang J, Jing Y, Liu Z, Hammock BD, Chen G. Chen Y, et al. Among authors: cao r. J Med Chem. 2024 Feb 8;67(3):2095-2117. doi: 10.1021/acs.jmedchem.3c02006. Epub 2024 Jan 18. J Med Chem. 2024. PMID: 38236416

6

2,2- dimethylbenzopyran derivatives containing pyridone structural fragments as selective dual-targeting inhibitors of HIF-1α and EZH2 for the treatment of lung cancer.

Xu H, Zhang J, Zhuang J, Chen Y, Chen L, Wang J, Cao R, Liu F, Wang K, Zhang X, Wang L, Chen G. Xu H, et al. Among authors: cao r. Bioorg Chem. 2024 Jun;147:107419. doi: 10.1016/j.bioorg.2024.107419. Epub 2024 Apr 30. Bioorg Chem. 2024. PMID: 38703440

7

The synthesis and bioactivities of ROCK2 inhibitors with 1,2-dithiolan-3-yl motif.

Cao R, Du F, Liu Z, Cai P, Qi M, Xiao W, Bao X, Chen G. Cao R, et al. RSC Med Chem. 2024 Aug 1;15(10):3576-96. doi: 10.1039/d4md00438h. Online ahead of print. RSC Med Chem. 2024. PMID: 39268077 Free article.

8

Mechanism of anti-AD action of OAB-14 by enhancing the function of glymphatic system.

Zhang X, Cao R, Zhu C, Yang L, Zheng N, Ji W, Liu P, Chi T, Ji X, Zheng Z, Chen G, Zou L. Zhang X, et al. Among authors: cao r. Neurochem Int. 2023 Oct 27:105633. doi: 10.1016/j.neuint.2023.105633. Online ahead of print. Neurochem Int. 2023. PMID: 39491236

9

An analysis of vitamin K status in Chinese healthy children aged 0-18 years.

Liu J, Chen L, Guo C, Feng Q, Cao R, Liu P, Wu Y, Song W, Lin J. Liu J, et al. Among authors: cao r. BMC Pediatr. 2024 Nov 6;24(1):703. doi: 10.1186/s12887-024-05195-y. BMC Pediatr. 2024. PMID: 39506667 Free article.

10

Triptolide induces hepatotoxicity by promoting ferroptosis through Nrf2 degradation.

Guo L, Yang Y, Ma J, Xiao M, Cao R, Xi Y, Li T, Huang T, Yan M. Guo L, et al. Among authors: cao r. Cell Biol Toxicol. 2024 Nov 6;40(1):94. doi: 10.1007/s10565-024-09930-0. Cell Biol Toxicol. 2024. PMID: 39503881

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