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Page 1
Cancer detection in clinical practice and using blood-based liquid biopsy: A retrospective audit of over 350 dogs.
Flory A, McLennan L, Peet B, Kroll M, Stuart D, Brown D, Stuebner K, Phillips B, Coomber BL, Woods JP, Miller M, Tripp CD, Wolf-Ringwall A, Kruglyak KM, McCleary-Wheeler AL, Phelps-Dunn A, Wong LK, Warren CD, Brandstetter G, Rosentel MC, DiMarzio LR, O'Kell AL, Cohen TA, Grosu DS, Chibuk J, Tsui DWY, Chorny I, Rafalko JM. Flory A, et al. Among authors: mccleary wheeler al. J Vet Intern Med. 2023 Jan;37(1):258-267. doi: 10.1111/jvim.16616. Epub 2023 Jan 20. J Vet Intern Med. 2023. PMID: 36661398 Free PMC article.
Age at cancer diagnosis by breed, weight, sex, and cancer type in a cohort of more than 3,000 dogs: Determining the optimal age to initiate cancer screening in canine patients.
Rafalko JM, Kruglyak KM, McCleary-Wheeler AL, Goyal V, Phelps-Dunn A, Wong LK, Warren CD, Brandstetter G, Rosentel MC, DiMarzio L, McLennan LM, O'Kell AL, Cohen TA, Grosu DS, Chibuk J, Tsui DWY, Chorny I, Flory A. Rafalko JM, et al. Among authors: mccleary wheeler al. PLoS One. 2023 Feb 1;18(2):e0280795. doi: 10.1371/journal.pone.0280795. eCollection 2023. PLoS One. 2023. PMID: 36724177 Free PMC article.
Clinical experience with next-generation sequencing-based liquid biopsy testing for cancer detection in dogs: a review of 1,500 consecutive clinical cases.
O'Kell AL, Lytle KM, Cohen TA, Wong LK, Sandford E, Rafalko JM, Brandstetter G, DiMarzio LR, Phelps-Dunn A, Rosentel MC, Warren CD, McCleary-Wheeler AL, Fiaux PC, Marass F, Marshall MA, Ruiz-Perez CA, Kruglyak KM, Tynan JA, Hicks SC, Grosu DS, Chibuk J, Chorny I, Tsui DWY, Flory A. O'Kell AL, et al. Among authors: mccleary wheeler al. J Am Vet Med Assoc. 2023 Mar 17;261(6):827-836. doi: 10.2460/javma.22.11.0526. Print 2023 Jun 1. J Am Vet Med Assoc. 2023. PMID: 36965477 Review.
Detection of Age-Related Somatic Alterations in Canine Blood Using Next-Generation Sequencing-Based Liquid Biopsy: An Analysis of over 4800 Dogs.
Kruglyak KM, O'Kell AL, Cohen TA, Marshall MA, Ruiz-Perez CA, Marass F, Tynan JA, Hicks SC, Lytle KM, Phelps-Dunn A, Brandstetter G, Warren CD, DiMarzio LR, Rosentel MC, Wong LK, McLennan LM, Rafalko JM, Grosu DS, Chibuk J, Chorny I, McCleary-Wheeler AL, Flory A, Tsui DWY. Kruglyak KM, et al. Among authors: mccleary wheeler al. Vet Sci. 2023 Jul 11;10(7):455. doi: 10.3390/vetsci10070455. Vet Sci. 2023. PMID: 37505860 Free PMC article.
Effects of neoadjuvant zoledronate and radiation therapy on cell survival, cell cycle distribution, and clinical status in canine osteosarcoma.
Norquest CJ, Rogic A, Gimotty PA, Maitz CA, Rindt H, Ashworth HL, Bryan JN, Donnelly LL, McCleary-Wheeler AL, Flesner BK. Norquest CJ, et al. Among authors: mccleary wheeler al. Front Vet Sci. 2024 Jan 31;11:1237084. doi: 10.3389/fvets.2024.1237084. eCollection 2024. Front Vet Sci. 2024. PMID: 38362299 Free PMC article.
Next-generation sequencing-based liquid biopsy may be used for detection of residual disease and cancer recurrence monitoring in dogs.
McCleary-Wheeler AL, Fiaux PC, Flesner BK, Ruiz-Perez CA, McLennan LM, Tynan JA, Hicks SC, Rafalko JM, Grosu DS, Chibuk J, O'Kell AL, Cohen TA, Chorny I, Tsui DWY, Kruglyak KM, Flory A. McCleary-Wheeler AL, et al. Am J Vet Res. 2023 Dec 28:1-8. doi: 10.2460/ajvr.23.07.0163. Online ahead of print. Am J Vet Res. 2023. PMID: 38150822 Free article.
Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas.
Shah SB, Carlson CR, Lai K, Zhong Z, Marsico G, Lee KM, Félix Vélez NE, Abeles EB, Allam M, Hu T, Walter LD, Martin KE, Gandhi K, Butler SD, Puri R, McCleary-Wheeler AL, Tam W, Elemento O, Takata K, Steidl C, Scott DW, Fontan L, Ueno H, Cosgrove BD, Inghirami G, García AJ, Coskun AF, Koff JL, Melnick A, Singh A. Shah SB, et al. Among authors: mccleary wheeler al. Nat Mater. 2023 Apr;22(4):511-523. doi: 10.1038/s41563-023-01495-3. Epub 2023 Mar 16. Nat Mater. 2023. PMID: 36928381 Free PMC article.
Clinical validation of a next-generation sequencing-based multi-cancer early detection "liquid biopsy" blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study.
Flory A, Kruglyak KM, Tynan JA, McLennan LM, Rafalko JM, Fiaux PC, Hernandez GE, Marass F, Nakashe P, Ruiz-Perez CA, Fath DM, Jennings T, Motalli-Pepio R, Wotrang K, McCleary-Wheeler AL, Lana S, Phillips B, Flesner BK, Leibman NF, LaDue T, Tripp CD, Coomber BL, Woods JP, Miller M, Aiken SW, Wolf-Ringwall A, Borgatti A, Kraska K, Thomson CB, Kosanovich Cahalane A, Murray RL, Kisseberth WC, Camps-Palau MA, Floch F, Beaudu-Lange C, Klajer-Peres A, Keravel O, Fribourg-Blanc LA, Mazetier PC, Marco A, McLeod MB, Portillo E, Clark TS, Judd S, Feinberg CK, Benitez M, Runyan C, Hackett L, Lafey S, Richardson D, Vineyard S, Tefend Campbell M, Dharajiya N, Jensen TJ, van den Boom D, Diaz LA Jr, Grosu DS, Polk A, Marsal K, Hicks SC, Lytle KM, Holtvoigt L, Chibuk J, Chorny I, Tsui DWY. Flory A, et al. Among authors: mccleary wheeler al. PLoS One. 2022 Apr 26;17(4):e0266623. doi: 10.1371/journal.pone.0266623. eCollection 2022. PLoS One. 2022. PMID: 35471999 Free PMC article.
Editorial: Comparative Oncology-Advances in Veterinary Molecular Oncology.
Meichner K, McCleary-Wheeler AL, Mochizuki H, Stokol T. Meichner K, et al. Among authors: mccleary wheeler al. Front Vet Sci. 2022 Jan 12;8:812856. doi: 10.3389/fvets.2021.812856. eCollection 2021. Front Vet Sci. 2022. PMID: 35097056 Free PMC article. No abstract available.
28 results