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SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth-onset type 2 diabetes.
Schaub JA, AlAkwaa FM, McCown PJ, Naik AS, Nair V, Eddy S, Menon R, Otto EA, Demeke D, Hartman J, Fermin D, O'Connor CL, Subramanian L, Bitzer M, Harned R, Ladd P, Pyle L, Pennathur S, Inoki K, Hodgin JB, Brosius FC 3rd, Nelson RG, Kretzler M, Bjornstad P. Schaub JA, et al. Among authors: o connor cl. J Clin Invest. 2023 Mar 1;133(5):e164486. doi: 10.1172/JCI164486. J Clin Invest. 2023. PMID: 36637914 Free PMC article.
MicroRNA-21 in glomerular injury.
Lai JY, Luo J, O'Connor C, Jing X, Nair V, Ju W, Randolph A, Ben-Dov IZ, Matar RN, Briskin D, Zavadil J, Nelson RG, Tuschl T, Brosius FC 3rd, Kretzler M, Bitzer M. Lai JY, et al. J Am Soc Nephrol. 2015 Apr;26(4):805-16. doi: 10.1681/ASN.2013121274. Epub 2014 Aug 21. J Am Soc Nephrol. 2015. PMID: 25145934 Free PMC article. Clinical Trial.
Glomerular Aging and Focal Global Glomerulosclerosis: A Podometric Perspective.
Hodgin JB, Bitzer M, Wickman L, Afshinnia F, Wang SQ, O'Connor C, Yang Y, Meadowbrooke C, Chowdhury M, Kikuchi M, Wiggins JE, Wiggins RC. Hodgin JB, et al. J Am Soc Nephrol. 2015 Dec;26(12):3162-78. doi: 10.1681/ASN.2014080752. Epub 2015 Jun 2. J Am Soc Nephrol. 2015. PMID: 26038526 Free PMC article.
Organoid single cell profiling identifies a transcriptional signature of glomerular disease.
Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, O'Connor C, Luo J, Nair V, Cebrian C, Spence JR, Bitzer M, Troyanskaya OG, Hodgin JB, Wiggins RC, Freedman BS, Kretzler M; European Renal cDNA Bank (ERCB); Nephrotic Syndrome Study Network (NEPTUNE). Harder JL, et al. JCI Insight. 2019 Jan 10;4(1):e122697. doi: 10.1172/jci.insight.122697. JCI Insight. 2019. PMID: 30626756 Free PMC article.
Hypertension induces glomerulosclerosis in phospholipase C-ε1 deficiency.
Atchison DK, O'Connor CL, Menon R, Otto EA, Ganesh SK, Wiggins RC, Smrcka AV, Bitzer M. Atchison DK, et al. Am J Physiol Renal Physiol. 2020 May 1;318(5):F1177-F1187. doi: 10.1152/ajprenal.00541.2019. Epub 2020 Mar 30. Am J Physiol Renal Physiol. 2020. PMID: 32223311 Free PMC article.
Endoplasmic reticulum-associated degradation is required for nephrin maturation and kidney glomerular filtration function.
Yoshida S, Wei X, Zhang G, O'Connor CL, Torres M, Zhou Z, Lin L, Menon R, Xu X, Zheng W, Xiong Y, Otto E, Tang CA, Hua R, Verma R, Mori H, Zhang Y, Hu CA, Liu M, Garg P, Hodgin JB, Sun S, Bitzer M, Qi L. Yoshida S, et al. Among authors: o connor cl. J Clin Invest. 2021 Apr 1;131(7):e143988. doi: 10.1172/JCI143988. J Clin Invest. 2021. PMID: 33591954 Free PMC article.
30 results