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SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth-onset type 2 diabetes.
Schaub JA, AlAkwaa FM, McCown PJ, Naik AS, Nair V, Eddy S, Menon R, Otto EA, Demeke D, Hartman J, Fermin D, O'Connor CL, Subramanian L, Bitzer M, Harned R, Ladd P, Pyle L, Pennathur S, Inoki K, Hodgin JB, Brosius FC 3rd, Nelson RG, Kretzler M, Bjornstad P. Schaub JA, et al. Among authors: inoki k. J Clin Invest. 2023 Mar 1;133(5):e164486. doi: 10.1172/JCI164486. J Clin Invest. 2023. PMID: 36637914 Free PMC article.
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL. Alexander A, et al. Among authors: inoki k. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4153-8. doi: 10.1073/pnas.0913860107. Epub 2010 Feb 16. Proc Natl Acad Sci U S A. 2010. PMID: 20160076 Free PMC article.
Critical roles for the TSC-mTOR pathway in β-cell function.
Mori H, Inoki K, Opland D, Münzberg H, Villanueva EC, Faouzi M, Ikenoue T, Kwiatkowski DJ, Macdougald OA, Myers MG Jr, Guan KL. Mori H, et al. Among authors: inoki k. Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1013-22. doi: 10.1152/ajpendo.00262.2009. Epub 2009 Aug 18. Am J Physiol Endocrinol Metab. 2009. PMID: 19690069 Free PMC article.
Loss of AMPKα2 Impairs Hedgehog-Driven Medulloblastoma Tumorigenesis.
Zhang H, Kuick R, Park SS, Peabody C, Yoon J, Fernández EC, Wang J, Thomas D, Viollet B, Inoki K, Camelo-Piragua S, Rual JF. Zhang H, et al. Among authors: inoki k. Int J Mol Sci. 2018 Oct 23;19(11):3287. doi: 10.3390/ijms19113287. Int J Mol Sci. 2018. PMID: 30360486 Free PMC article.
117 results