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Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling.
Yun J, Hansen S, Morris O, Madden DT, Libeu CP, Kumar AJ, Wehrfritz C, Nile AH, Zhang Y, Zhou L, Liang Y, Modrusan Z, Chen MB, Overall CC, Garfield D, Campisi J, Schilling B, Hannoush RN, Jasper H. Yun J, et al. Among authors: hannoush rn. Nat Commun. 2023 Jan 11;14(1):156. doi: 10.1038/s41467-022-35487-9. Nat Commun. 2023. PMID: 36631445 Free PMC article.
Inhibition of Wnt signaling by Dishevelled PDZ peptides.
Zhang Y, Appleton BA, Wiesmann C, Lau T, Costa M, Hannoush RN, Sidhu SS. Zhang Y, et al. Among authors: hannoush rn. Nat Chem Biol. 2009 Apr;5(4):217-9. doi: 10.1038/nchembio.152. Epub 2009 Mar 1. Nat Chem Biol. 2009. PMID: 19252499
Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.
Stanger K, Steffek M, Zhou L, Pozniak CD, Quan C, Franke Y, Tom J, Tam C, Krylova I, Elliott JM, Lewcock JW, Zhang Y, Murray J, Hannoush RN. Stanger K, et al. Among authors: hannoush rn. Nat Chem Biol. 2012 Jul;8(7):655-60. doi: 10.1038/nchembio.967. Epub 2012 Jun 10. Nat Chem Biol. 2012. PMID: 22683611
Fatty acylation of Wnt proteins.
Nile AH, Hannoush RN. Nile AH, et al. Among authors: hannoush rn. Nat Chem Biol. 2016 Feb;12(2):60-9. doi: 10.1038/nchembio.2005. Nat Chem Biol. 2016. PMID: 26784846
A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.
Nile AH, de Sousa E Melo F, Mukund S, Piskol R, Hansen S, Zhou L, Zhang Y, Fu Y, Gogol EB, Kömüves LG, Modrusan Z, Angers S, Franke Y, Koth C, Fairbrother WJ, Wang W, de Sauvage FJ, Hannoush RN. Nile AH, et al. Among authors: hannoush rn. Nat Chem Biol. 2018 Jun;14(6):582-590. doi: 10.1038/s41589-018-0035-2. Epub 2018 Apr 9. Nat Chem Biol. 2018. PMID: 29632413
Fatty acid recognition in the Frizzled receptor family.
Nile AH, Hannoush RN. Nile AH, et al. Among authors: hannoush rn. J Biol Chem. 2019 Jan 11;294(2):726-736. doi: 10.1074/jbc.REV118.005205. Epub 2018 Dec 10. J Biol Chem. 2019. PMID: 30530496 Free PMC article. Review.
69 results