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Unveiling the multifaceted landscape of N-glycosylation in antibody variable domains: Insights and implications.
Melo-Braga MN, Carvalho MB, Ferreira MCE, Lavinder J, Abbasi A, Palmisano G, Thaysen-Andersen M, Sajadi MM, Ippolito GC, Felicori LF. Melo-Braga MN, et al. Among authors: sajadi mm. Int J Biol Macromol. 2024 Feb;257(Pt 1):128362. doi: 10.1016/j.ijbiomac.2023.128362. Epub 2023 Nov 28. Int J Biol Macromol. 2024. PMID: 38029898 Free PMC article.
A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV.
Sajadi MM, Abbasi A, Tehrani ZR, Siska C, Clark R, Chi W, Seaman MS, Mielke D, Wagh K, Liu Q, Jumpa T, Ketchem RR, Nguyen DN, Tolbert WD, Pierce BG, Atkinson B, Deming D, Sprague M, Asakawa A, Ferrer D, Dunn Y, Calvillo S, Yin R, Guest JD, Korber B, Mayer BT, Sato AH, Ouyang X, Foulke S, Habibzadeh P, Karimi M, Aslanabadi A, Hojabri M, Saadat S, Zareidoodeji R, Kędzior M, Pozharski E, Heredia A, Montefiori D, Ferrari G, Pazgier M, Lewis GK, Jardine JG, Lusso P, DeVico A. Sajadi MM, et al. bioRxiv [Preprint]. 2024 Oct 17:2024.10.14.618178. doi: 10.1101/2024.10.14.618178. bioRxiv. 2024. PMID: 39464103 Free PMC article. Preprint.
Early elevated IFNα is a key mediator of HIV pathogenesis.
Buanec HL, Schiavon V, Merandet M, How-Kit A, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Song H, Sajadi MM, Kottilil S, Gallo RC, Zagury D. Buanec HL, et al. Among authors: sajadi mm. Commun Med (Lond). 2024 Mar 19;4(1):53. doi: 10.1038/s43856-024-00454-6. Commun Med (Lond). 2024. PMID: 38504106 Free PMC article.
IFNα induces CCR5 in CD4+ T cells of HIV patients causing pathogenic elevation.
Le Buanec H, Schiavon V, Merandet M, How-Kit A, Song H, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Sajadi MM, Kottilil S, Zagury D, Gallo RC. Le Buanec H, et al. Among authors: sajadi mm. Commun Med (Lond). 2024 Mar 19;4(1):52. doi: 10.1038/s43856-024-00453-7. Commun Med (Lond). 2024. PMID: 38504093 Free PMC article.
Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.
Streblow DN, Hirsch AJ, Stanton JJ, Lewis AD, Colgin L, Hessell AJ, Kreklywich CN, Smith JL, Sutton WF, Chauvin D, Woo J, Bimber BN, LeBlanc CN, Acharya SN, O'Roak BJ, Sardar H, Sajadi MM, Tehrani ZR, Walter MR, Martinez-Sobrido L, Kobie JJ, Reader RJ, Olstad KJ, Hobbs TR, Saphire EO, Schendel SL, Carnahan RH, Knoch J, Branco LM, Crowe JE Jr, Van Rompay KKA, Lovalenti P, Vu Truong, Forthal DN, Haigwood NL. Streblow DN, et al. Among authors: sajadi mm. Nat Commun. 2023 Nov 3;14(1):7062. doi: 10.1038/s41467-023-42440-x. Nat Commun. 2023. PMID: 37923717 Free PMC article.
86 results