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Translational analysis and final efficacy of the AVETUX trial - Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer.
Tintelnot J, Ristow I, Sauer M, Simnica D, Schultheiß C, Scholz R, Goekkurt E, von Wenserski L, Willscher E, Paschold L, Lorenzen S, Riera-Knorrenschild J, Depenbusch R, Ettrich TJ, Dörfel S, Al-Batran SE, Karthaus M, Pelzer U, Hinke A, Bauer M, Massa C, Seliger B, Wickenhauser C, Bokemeyer C, Hegewisch-Becker S, Binder M, Stein A. Tintelnot J, et al. Among authors: willscher e. Front Oncol. 2022 Dec 20;12:993611. doi: 10.3389/fonc.2022.993611. eCollection 2022. Front Oncol. 2022. PMID: 36605436 Free PMC article.
A20 haploinsufficiency disturbs immune homeostasis and drives the transformation of lymphocytes with permissive antigen receptors.
Schultheiß C, Paschold L, Mohebiany AN, Escher M, Kattimani YM, Müller M, Schmidt-Barbo P, Mensa-Vilaró A, Aróstegui JI, Boursier G, de Moreuil C, Hautala T, Willscher E, Jonas H, Chinchuluun N, Grosser B, Märkl B, Klapper W, Oommen PT, Gössling K, Hoffmann K, Tiegs G, Czernilofsky F, Dietrich S, Freeman A, Schwartz DM, Waisman A, Aksentijevich I, Binder M. Schultheiß C, et al. Among authors: willscher e. Sci Adv. 2024 Aug 23;10(34):eadl3975. doi: 10.1126/sciadv.adl3975. Epub 2024 Aug 21. Sci Adv. 2024. PMID: 39167656 Free PMC article.
B cells expressing mutated IGHV1-69-encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection.
Schultheiß C, Willscher E, Paschold L, Ackermann C, Escher M, Scholz R, Knapp M, Lützkendorf J, Müller LP, Schulze Zur Wiesch J, Binder M. Schultheiß C, et al. Among authors: willscher e. Hepatol Commun. 2024 Jul 31;8(8):e0503. doi: 10.1097/HC9.0000000000000503. eCollection 2024 Aug 1. Hepatol Commun. 2024. PMID: 39082968 Free article.
SARS-CoV-2 vaccination may mitigate dysregulation of IL-1/IL-18 and gastrointestinal symptoms of the post-COVID-19 condition.
Fischer C, Willscher E, Paschold L, Gottschick C, Klee B, Diexer S, Bosurgi L, Dutzmann J, Sedding D, Frese T, Girndt M, Hoell JI, Gekle M, Addo MM, Schulze Zur Wiesch J, Mikolajczyk R, Binder M, Schultheiß C. Fischer C, et al. Among authors: willscher e. NPJ Vaccines. 2024 Feb 5;9(1):23. doi: 10.1038/s41541-024-00815-1. NPJ Vaccines. 2024. PMID: 38316833 Free PMC article.
SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters.
Groß E, Hilger RA, Schümann FL, Bauer M, Bouska A, Rohde C, Willscher E, Lützkendorf J, Müller LP, Edemir B, Mueller T, Herling M, Binder M, Wickenhauser C, Iqbal J, Posern G, Weber T. Groß E, et al. Among authors: willscher e. Cancers (Basel). 2023 Jun 3;15(11):3043. doi: 10.3390/cancers15113043. Cancers (Basel). 2023. PMID: 37297005 Free PMC article.
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