Lei X - Search Results

1

Biomimetic Total Synthesis and the Biological Evaluation of Natural Product (-)-Fargesone A as a Novel FXR Agonist.

Guo F, Chen K, Dong H, Hu D, Gao Y, Liu C, Laphookhieo S, Lei X. Guo F, et al. Among authors: lei x. JACS Au. 2022 Dec 7;2(12):2830-2838. doi: 10.1021/jacsau.2c00600. eCollection 2022 Dec 26. JACS Au. 2022. PMID: 36590256 Free PMC article.

2

Divergent Total Syntheses of (-)-Huperzine Q, (+)-Lycopladine B, (+)-Lycopladine C, and (-)-4-epi-Lycopladine D.

Hong B, Hu D, Wu J, Zhang J, Li H, Pan Y, Lei X. Hong B, et al. Among authors: lei x. Chem Asian J. 2017 Jul 4;12(13):1557-1567. doi: 10.1002/asia.201700364. Epub 2017 Jun 8. Chem Asian J. 2017. PMID: 28440575

3

Biomimetic Synthesis of Rhytidenone A and Mode of Action of Cytotoxic Rhytidenone F.

Yue Z, Lam HC, Chen K, Siridechakorn I, Liu Y, Pudhom K, Lei X. Yue Z, et al. Among authors: lei x. Angew Chem Int Ed Engl. 2020 Mar 2;59(10):4115-4120. doi: 10.1002/anie.201914257. Epub 2020 Jan 27. Angew Chem Int Ed Engl. 2020. PMID: 31868281

4

Styryllactones from Goniothalamus tamirensis.

Meesakul P, Jaidee W, Richardson C, Andersen RJ, Patrick BO, Willis AC, Muanprasat C, Wang J, Lei X, Hadsadee S, Jungsuttiwong S, Pyne SG, Laphookhieo S. Meesakul P, et al. Among authors: lei x. Phytochemistry. 2020 Mar;171:112248. doi: 10.1016/j.phytochem.2019.112248. Epub 2020 Jan 6. Phytochemistry. 2020. PMID: 31918304

5

Protecting-Group-Free Syntheses of ent-Kaurane Diterpenoids: [3+2+1] Cycloaddition/Cycloalkenylation Approach.

Wang J, Hong B, Hu D, Kadonaga Y, Tang R, Lei X. Wang J, et al. Among authors: lei x. J Am Chem Soc. 2020 Feb 5;142(5):2238-2243. doi: 10.1021/jacs.9b13722. Epub 2020 Jan 27. J Am Chem Soc. 2020. PMID: 31968171

6

Click-based amplification: designed to facilitate various target labelling modes with ultralow background amplification.

Bai J, Guo F, Li M, Li Y, Lei X. Bai J, et al. Among authors: lei x. RSC Chem Biol. 2021 Mar 20;2(3):906-916. doi: 10.1039/d1cb00002k. eCollection 2021 Jun 1. RSC Chem Biol. 2021. PMID: 34458817 Free PMC article.

7

A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration.

Du J, Zheng L, Gao P, Yang H, Yang WJ, Guo F, Liang R, Feng M, Wang Z, Zhang Z, Bai L, Bu Y, Xing S, Zheng W, Wang X, Quan L, Hu X, Wu H, Chen Z, Chen L, Wei K, Zhang Z, Zhu X, Zhang X, Tu Q, Zhao SM, Lei X, Xiong JW. Du J, et al. Among authors: lei x. Cell Stem Cell. 2022 Apr 7;29(4):545-558.e13. doi: 10.1016/j.stem.2022.03.009. Cell Stem Cell. 2022. PMID: 35395187 Free article.

8

Structural basis of TRPV3 inhibition by an antagonist.

Fan J, Hu L, Yue Z, Liao D, Guo F, Ke H, Jiang D, Yang Y, Lei X. Fan J, et al. Among authors: lei x. Nat Chem Biol. 2023 Jan;19(1):81-90. doi: 10.1038/s41589-022-01166-5. Epub 2022 Oct 27. Nat Chem Biol. 2023. PMID: 36302896

9

Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.

Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J. Zhong Q, et al. Among authors: lei x. Cell Discov. 2022 Dec 22;8(1):137. doi: 10.1038/s41421-022-00502-2. Cell Discov. 2022. PMID: 36550107 Free PMC article.

10

Natural Product 2-Oxokolavenol Is a Novel FXR Agonist.

Guo F, Gao Y, Li X, Lei X. Guo F, et al. Among authors: lei x. Molecules. 2022 Dec 16;27(24):8968. doi: 10.3390/molecules27248968. Molecules. 2022. PMID: 36558100 Free PMC article.

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