Alvarez MJ - Search Results

1

Network-based assessment of HDAC6 activity predicts preclinical and clinical responses to the HDAC6 inhibitor ricolinostat in breast cancer.

Zeleke TZ, Pan Q, Chiuzan C, Onishi M, Li Y, Tan H, Alvarez MJ, Honan E, Yang M, Chia PL, Mukhopadhyay P, Kelly S, Wu R, Fenn K, Trivedi MS, Accordino M, Crew KD, Hershman DL, Maurer M, Jones S, High A, Peng J, Califano A, Kalinsky K, Yu J, Silva J. Zeleke TZ, et al. Among authors: alvarez mj. Nat Cancer. 2023 Feb;4(2):257-275. doi: 10.1038/s43018-022-00489-5. Epub 2022 Dec 30. Nat Cancer. 2023. PMID: 36585452 Free PMC article.

2

Dissecting the interface between signaling and transcriptional regulation in human B cells.

Wang K, Alvarez MJ, Bisikirska BC, Linding R, Basso K, Dalla Favera R, Califano A. Wang K, et al. Among authors: alvarez mj. Pac Symp Biocomput. 2009:264-75. Pac Symp Biocomput. 2009. PMID: 19209707 Free PMC article.

3

Genome-wide identification of post-translational modulators of transcription factor activity in human B cells.

Wang K, Saito M, Bisikirska BC, Alvarez MJ, Lim WK, Rajbhandari P, Shen Q, Nemenman I, Basso K, Margolin AA, Klein U, Dalla-Favera R, Califano A. Wang K, et al. Among authors: alvarez mj. Nat Biotechnol. 2009 Sep;27(9):829-39. doi: 10.1038/nbt.1563. Epub 2009 Sep 9. Nat Biotechnol. 2009. PMID: 19741643 Free PMC article.

4

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

Basso K, Saito M, Sumazin P, Margolin AA, Wang K, Lim WK, Kitagawa Y, Schneider C, Alvarez MJ, Califano A, Dalla-Favera R. Basso K, et al. Among authors: alvarez mj. Blood. 2010 Feb 4;115(5):975-84. doi: 10.1182/blood-2009-06-227017. Epub 2009 Dec 3. Blood. 2010. PMID: 19965633 Free PMC article.

5

The transcriptional network for mesenchymal transformation of brain tumours.

Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, Snyder EY, Sulman EP, Anne SL, Doetsch F, Colman H, Lasorella A, Aldape K, Califano A, Iavarone A. Carro MS, et al. Among authors: alvarez mj. Nature. 2010 Jan 21;463(7279):318-25. doi: 10.1038/nature08712. Epub 2009 Dec 23. Nature. 2010. PMID: 20032975 Free PMC article.

6

Correlating measurements across samples improves accuracy of large-scale expression profile experiments.

Alvarez MJ, Sumazin P, Rajbhandari P, Califano A. Alvarez MJ, et al. Genome Biol. 2009;10(12):R143. doi: 10.1186/gb-2009-10-12-r143. Epub 2009 Dec 30. Genome Biol. 2009. PMID: 20042104 Free PMC article.

7

Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling.

Kruithof-de Julio M, Alvarez MJ, Galli A, Chu J, Price SM, Califano A, Shen MM. Kruithof-de Julio M, et al. Among authors: alvarez mj. Development. 2011 Sep;138(18):3885-95. doi: 10.1242/dev.065656. Development. 2011. PMID: 21862554 Free PMC article.

8

Quantitative modeling of the terminal differentiation of B cells and mechanisms of lymphomagenesis.

Martínez MR, Corradin A, Klein U, Álvarez MJ, Toffolo GM, di Camillo B, Califano A, Stolovitzky GA. Martínez MR, et al. Among authors: alvarez mj. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2672-7. doi: 10.1073/pnas.1113019109. Epub 2012 Jan 30. Proc Natl Acad Sci U S A. 2012. PMID: 22308355 Free PMC article.

9

Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.

Aytes A, Mitrofanova A, Lefebvre C, Alvarez MJ, Castillo-Martin M, Zheng T, Eastham JA, Gopalan A, Pienta KJ, Shen MM, Califano A, Abate-Shen C. Aytes A, et al. Among authors: alvarez mj. Cancer Cell. 2014 May 12;25(5):638-651. doi: 10.1016/j.ccr.2014.03.017. Cancer Cell. 2014. PMID: 24823640 Free PMC article.

10

A systems approach to drug discovery in Alzheimer's disease.

Shelanski M, Shin W, Aubry S, Sims P, Alvarez MJ, Califano A. Shelanski M, et al. Among authors: alvarez mj. Neurotherapeutics. 2015 Jan;12(1):126-31. doi: 10.1007/s13311-014-0335-5. Neurotherapeutics. 2015. PMID: 25608936 Free PMC article. Review.

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