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Page 1
Weight Loss and Alzheimer's Disease in Down Syndrome.
Fleming V, Helsel BC, Ptomey LT, Rosas HD, Handen B, Laymon C, Christian BT, Head E, Mapstone M, Lai F, Krinsky-McHale S, Zaman S, Ances BM, Lee JH, Hartley SL; Alzheimer’s Biomarker Consortium –Down Syndrome (ABC-DS) Consortium. Fleming V, et al. Among authors: mapstone m. J Alzheimers Dis. 2023;91(3):1215-1227. doi: 10.3233/JAD-220865. J Alzheimers Dis. 2023. PMID: 36565120 Free PMC article.
Joint-label fusion brain atlases for dementia research in Down syndrome.
Queder N, Phelan MJ, Taylor L, Tustison N, Doran E, Hom C, Nguyen D, Lai F, Pulsifer M, Price J, Kreisl WC, Rosas HD, Krinsky-McHale S, Brickman AM, Yassa MA, Schupf N, Silverman W, Lott IT, Head E, Mapstone M, Keator DB; Alzheimer's Biomarkers Consortium. Queder N, et al. Among authors: mapstone m. Alzheimers Dement (Amst). 2022 May 25;14(1):e12324. doi: 10.1002/dad2.12324. eCollection 2022. Alzheimers Dement (Amst). 2022. PMID: 35634535 Free PMC article.
Plasma NT1-tau and Aβ42 correlate with age and cognitive function in two large Down syndrome cohorts.
Stern AM, Van Pelt KL, Liu L, Anderson AK, Ostaszewski B, Mapstone M, O'Bryant S, Petersen ME, Christian BT, Handen BL, Selkoe DJ, Schmitt F, Head E; Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) investigators. Stern AM, et al. Among authors: mapstone m. Alzheimers Dement. 2023 Dec;19(12):5755-5764. doi: 10.1002/alz.13382. Epub 2023 Jul 12. Alzheimers Dement. 2023. PMID: 37438872
Timing of Alzheimer's Disease by Intellectual Disability Level in Down Syndrome.
Hartley SL, Fleming V, Schworer EK, Peven J, Handen BL, Krinsky-McHale S, Hom C, Lee L, Tudorascu DL, Laymon C, Minhas D, Luo W, Cohen A, Zaman S, Ances BM, Mapstone M, Head E, Lai F, Rosas HD, Klunk W, Christian B; Alzheimer Biomarker Consortium-Down Syndrome. Hartley SL, et al. Among authors: mapstone m. J Alzheimers Dis. 2023;95(1):213-225. doi: 10.3233/JAD-230200. J Alzheimers Dis. 2023. PMID: 37482997 Free PMC article.
Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome.
Gorijala P, Aslam MM, Dang LT, Xicota L, Fernandez MV, Sung YJ, Fan KH, Feingold E, Surace EI, Chhatwal JP, Hom CL; Dominantly Inherited Alzheimer Network (DIAN), the Alzheimer's Disease Neuroimaging Initiative (ADNI); NIA-LOAD family study, for the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) Investigators; Hartley SL, Hassenstab J, Perrin RJ, Mapstone M, Zaman SH, Ances BM, Kamboh MI, Lee JH, Cruchaga C. Gorijala P, et al. Among authors: mapstone m. Alzheimers Dement. 2024 Feb;20(2):1038-1049. doi: 10.1002/alz.13506. Epub 2023 Oct 19. Alzheimers Dement. 2024. PMID: 37855447 Free PMC article.
Pathways linking pulse pressure to dementia in adults with Down syndrome.
Rizvi B, Lao PJ, Sathishkumar M, Taylor L, Queder N, McMillan L, Edwards N, Keator DB, Doran E, Hom C, Nguyen D, Rosas HD, Lai F, Schupf N, Gutierrez J, Silverman W, Lott IT, Mapstone M, Wilcock DM, Head E, Yassa MA, Brickman AM. Rizvi B, et al. Among authors: mapstone m. medRxiv [Preprint]. 2023 Oct 26:2023.10.26.23297625. doi: 10.1101/2023.10.26.23297625. medRxiv. 2023. Update in: Brain Commun. 2024 May 09;6(3):fcae157. doi: 10.1093/braincomms/fcae157. PMID: 37961444 Free PMC article. Updated. Preprint.
Neurofilament light chain concentration mediates the association between regional medial temporal lobe structure and memory in adults with Down syndrome.
DiProspero N, Sathishkumar M, Janecek J, Smith A, McMillan L, Petersen M, Tustison N, Keator DB, Doran E, Hom CL, Nguyen D, Andrews H, Krinsky-McHale S, Brickman AM, Rosas HD, Lai F, Head E, Mapstone M, Silverman W, Lott IT, O'Bryant S, Yassa MA. DiProspero N, et al. Among authors: mapstone m. Alzheimers Dement (Amst). 2024 Feb 12;16(1):e12542. doi: 10.1002/dad2.12542. eCollection 2024 Jan-Mar. Alzheimers Dement (Amst). 2024. PMID: 38348178 Free PMC article.
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS). Xicota L, et al. Among authors: mapstone me. Alzheimers Dement. 2024 Apr;20(4):2670-2679. doi: 10.1002/alz.13718. Epub 2024 Feb 21. Alzheimers Dement. 2024. PMID: 38380866 Free PMC article.
A pathway linking pulse pressure to dementia in adults with Down syndrome.
Rizvi B, Lao PJ, Sathishkumar M, Taylor L, Queder N, McMillan L, Edwards NC, Keator DB, Doran E, Hom C, Nguyen D, Rosas HD, Lai F, Schupf N, Gutierrez J, Silverman W, Lott IT, Mapstone M, Wilcock DM, Head E, Yassa MA, Brickman AM. Rizvi B, et al. Among authors: mapstone m. Brain Commun. 2024 May 9;6(3):fcae157. doi: 10.1093/braincomms/fcae157. eCollection 2024. Brain Commun. 2024. PMID: 38764776 Free PMC article.
Amyloid age and tau PET timeline to symptomatic Alzheimer's disease in Down syndrome.
Schworer EK, Zammit MD, Wang J, Handen BL, Betthauser T, Laymon CM, Tudorascu DL, Cohen AD, Zaman SH, Ances BM, Mapstone M, Head E, Klunk WE, Christian BT, Hartley SL; Alzheimer Biomarker Consortium – Down Syndrome (ABC-DS). Schworer EK, et al. Among authors: mapstone m. medRxiv [Preprint]. 2024 Aug 9:2024.08.08.24311702. doi: 10.1101/2024.08.08.24311702. medRxiv. 2024. PMID: 39211859 Free PMC article. Preprint.
132 results